Adrafinil is a nootropic stimulant supplement that is very similar to Modafinil. As a pro-drug of Modafinil, it actually metabolizes to Modafinil in the liver, which is why it’s actually a weaker, yet more dangerous alternative to Adrafinil. Since Adrafinil creates its effects via the liver, it puts a lot of strain on the organ, and as such can lead to Liver Toxicity. While it is often times cheaper than Modafinil, with increased risk of harm, Provigil is the far safer choice. Adrafinil is often used off-label (and purchased online by those self-medicating) for the treatment of ADHD.
Benefits of Adrafinil
Adrafinil, as a pro-drug of Modafinil, carries many of its same beneficial qualities. These include increased focus, better mood and memory throughout the day, heightened mental stamina, and increased productivity. Adrafinil is also often times known as Olmifon (an old brand name of the drug that is now only rarely sold.) Adrafinil is 100% legal to buy in the United States, and is sold by many nootropics companies on the web.
Whether or not Adrafinil can significantly benefit the effects and issues of ADHD enough to become a prescription, is still up for much debate. However, some clinical reserach is showing that the drug may be effective at improving focus and concentration long-term, and that it has few side effects. You can read up more on clinical trials regarding Adrafinil for ADHD here:
I can personally vouch for Adrafinil that it does in-fact help with focus, mood, memory and energy levels, but that it is significantly weaker than Modafinil, and is also a bit “dirtier,” because of its effects on the liver.
Adrafinil requires a higher dosage than Modafinil to achieve an effect, because it is a weaker drug. Typical dosages of Adrafinil range from 3-600 milligrams at a time, and usually has a maximum ceiling of 1200 milligrams (although this is really not recommended, as a fair amount of excess side effects can and probably will occur.) The lowest dosage of Adrafinil typically taken for effects is around 200 milligrams, anything lower than this and you most likely won’t feel anything. Adrafinil typically has a 3 to 1 ratio on Modafinil, meaning that 200 milligrams of Modafinil is the equivalent of 600 milligrams of Adrafinil. Always stick with the minimum effective dosage until you’ve seen how the drug affects you.
Adrafinil can have a number of unpleasant side effects if too high of a dosage is taken, or if it is taken too frequently. Because of this, Adrafinil is not recommended to be taken long-term. Side Effects of the drug can include
Loss of appetite
Withdrawal Symptoms upon ceasing use
Skin Rash (rare)
This is not a full list of side effects for Adrafinil. You may not experience any or all of these side effects when taking Adrafinil. While Adrafinil is typically sold in the form of powder, capsules are much safer since they have less of a risk of dosing error. Modafinil doesn’t have this issue as it is almost always sold in the form of tablets.
Adrafinil for ADHD
With regards for ADHD, my personal opinion on the matter is that Adrafinil can make a fantastic off-label treatment, at least in theory. Modafinil is prescribed off-label for ADHD, and since Adrafinil is a prodrug of Modafinil, it likely would carry over most of the same benefits for aiding attention deficits in its users.
Adrafinil vs Modafinil
When comparing Adrafinil vs Modafinil, always keep in mind a 3 to 1 ratio on the side of Modafinil (Provigil.) Modafinil is actually the stronger, cleaner and safer nootropic drug, and was recently deemed the “world’s first legitamite Smart Drug” in a number of clinical trials and tech bloggers. You can get more information about this here.
Research on Adrafinil
Adrafinil is actually lacking in research, which is why its not an FDA approved drug. However, as a pro-drug of Modafinil, a similar and more powerful nootropic, there is lots of research available on Modafinil, you can read up on the benefits and studies of the drug at the following links:
How Adrafinil can Successfully Benefit Many Symptoms of ADHD
Many of the symptoms of ADHD can be effectively managed by Adrafinil, including improved focus, mood, memory and energy levels (in those with hyperactivity Adrafinil can actually create a calming effect.) A supplement alternative to something prescribed off-label for ADHD, Adrafinil may just be the over the counter kick you’re looking for. In my opinion however, go with Modafinil, it’s much cleaner.