For those who need to stay up late, study, or have sleep apnea, drugs such as Armodafinil and Provigil (a.k.a. Modafinils) have been used. They treat certain health ailments such narcolepsy and sleep disorders by “waking up the neurotransmitters” of the brain. The difference is that one is used more; which is it?
For the most part, Armodafinil was produced in the U.S. by the pharmaceutical company Cephalon Inc. It was also approved by the U.S. Food and Drug Administration in 2007 of June.
Comparably, the drug Provigil had some difficulties in getting through some of the medical community experts and individuals who took it.
What is Provigil?
One of the prescriptions used by doctors to treat certain sleeping conditions or disorders is Provigil (also called Modafinil). It is used to help those having disorders such as sleep apnea or narcolepsy. Not only does it assist with helping those two but also with attention deficit hyperactivity disorder, and fatigue. Much debate continues with what causes this disorder in patients, current research and studies are testing it for other use. With the right treatment and medication, these sleep disorders can be treated through time.
Before use, it’s recommended that you tell your doctor if you have liver disease, angina (chest pain), kidney disease, a history of drug addiction, taking blood pressure medication, or a heart attack recently.
The benefits of Provigil is that it has a wakefulness-promoting agent which affects the brain. How it works is still unknown but there are certain chemicals in the brain which may affect individual’s sleeping patterns. Shift work sleeping disorders is another reason why a patient would want this prescription. Also, the benefits of it beat caffeinated drinks in place of modafinils, such as Provigil.
One of the main benefits of the drug is improvement of the functioning of the brain’s frontal lobe. With the ability to stimulate and improve this functioning, it does carry different standard stimulants in it’s ingredients. This is why it’s important to follow the medication guide appropriately.
Interesting enough, Provigil (or modafinil) has been prescribed to treat cocaine addiction. Yet, since studies are still going on currently and are relatively small, it hasn’t been approved just yet.
Another benefit is for weight loss, yet, it hasn’t been approved for this purpose either. The use of weight loss must be warned that excessive calore deficiency can often lead to impaired mental function and other negative effects.
Naturally, using such medications that have been prescribed by your doctor has dosing instructions. Going by the instructions is critical to any patient; using Provigil as directed is what the patient is responsible for without over usage or abuse to the drug. The information sheet or Medication Guide should be read carefully and it’s recommended to read for every refill. There could be changes or alterations to the dosage.
-For adults with Narcolepsy: 200 mg orally daily in the morning
-Normal dosage for adults using it for Obstructive Sleep Apnea or Hypopnea Syndrome: 200 mg orally daily in the morning
-Normal adult dosage for Shift Work-Sleep Disorders: 200 mg orally, daily; 1 hour before beginning the work shift.
-Normal pediatric dosage for Attention Deficit Disorder: Not FDA approved. (See research)
-For Children: Less than 30 kg: 200-340 mg once daily and
for Children: more than 30 kg: 300-425 mg
*(More on Dosage Information (in more detail).
You can also ask your doctor any questions you may have about how to use Provigil.
Long Term Use and Research
Provigil has been known to cause addiction in users. Nevertheless, this medication is considered a dependent drug in certain individuals. These individuals taking the drug long term may become dependent on it; so the dependency risks versus benefits of the medication before taking it long term should be noted with your physician.
For more Research, checkout the following links:
Short Term Use
If taking the drug to treat any of the above disorders, stopping or taking it in short term use can have effects to the individual. Seizures can take place for some individuals if stopping the use of intake suddenly after a short amount of time. It should also be take, once taken, at maximum of 12 weeks for it’s effective usage.
Use for narcolepsy
Narcolepsy patients can use the modafinil medications and since Provigil was first approved by the Federal Drug Administration as an ideal treatment for narcolepsy it was fine. Although, currently, there’s still debate, because of the side effects. It became aware in the medical community that it’s more of a tolerant build-up than treatment to the disorder. Research is still continuing for the use of Provigil to treat narcolepsy, as the debates go on.
There are some unexpected effects of Modafinil. It is that it can lead to enhanced sensory perceptions. With the right frame of mind, it’s been seen as a good effect. Compared to a number of other Nootropic supplements, it can be rather pleasurable when used with that right frame of mind; so everyone is different because not everyone “thinks” the same. What one person my feel is negative, another may feel is positive. The debate can go on when it comes to agreeing with the use of Provigil because of this subject matter.
Some nootropic use works internally which can address cognitive elements in order to improve memory and thereby enhancing it as well. It also can help mental performance, focus, concentration, clarity, and ultimately, maximize the productivity of a person with great benefits. It’s considered “brain fuel” to those that it works for.
(It’s ingredients for the Provigil tablets include either: 100mg or 200 mg of Modafinil, magnesium stearate, lactose monohydrate, povidone, croscarmellose, microcrystalline, and pregelatinized starch.)
The reported effects of Provigil, or modafinil are reviewed as a better energy booster and the levels of alertness is ideal for healthy adults. Individuals who’ve suffered sleep disorders do benefit, but some of the individuals which have been reviewed say it benefits all in all.
Nevertheless, it is different for everyone. Normally, it will feel like it’s working within 30 to 45 minutes after taking it. Some reviewers have said taking it when waking up is essential because it’s a “booster”. One reviewer mentioned that taking is similar to drinking coffee in the morning; since they had a hardd time waking up, it makes sense. Some other reviewers say that they feel refresher in the morning.
Some students who have taken Provigil suggest that it’s great for studying and taking exams. Hence, a sleep aid?
Additionally, one former college football player claimed that he’s had narcolepsy for years and has been on Provigil for over a year; starting with the lowest dosage and 3-6 months later, he’s at the highest dosage possible. With little side effects, it does curb his appetite, and now feels he’s immune to the medicine since the impact is lesser now. He now takes 4 pills a day. Although, he’s not falling asleep as much either, he feels no energy still; bottom line, he feels it’s not working for him.
So, in general, Provigil can be beneficial for those more with sleep apnea and those who have trouble sleeping; this was found more affective than using it for narcolepsy.
Provigil can cause skin reactions that may be severe enough to need treatment in a hospital. Stop taking this medicine and get emergency medical help if you have a skin rash or hives, blisters or peeling, mouth sores, trouble breathing or swallowing, fever, swelling in your legs, dark urine, yellowing of your skin or eyes, or swelling in your face.
Also, some of the side effects due to taking the medication are anorexia, xerostomia, headaches, and nausea. Here is a list of adverse effects.
-Blurred vision, other vision changes
-Black, Tarry stools
-Problems with memory
-shortness of breath
-rapidly changed moods
-chills or fever
-clumsiness or unsteadiness
-increased urination and thirst
-uncontrolled bleeding, bruising
-uncontrolled movements of the face or mouth, tongue
-unusual tiredness or weakness
Symptoms of overdose: Be alert when taking this drug also; these are symptoms of overdosage: irritability, excitement, fast or pounding heartbeat, increased blood pressure and trouble sleeping.
Some Provigil side effects may not need any medical attention, but as your body gets used to it, the side effects may clear up or disappear. Your doctor may be able to help you reduce them so communicating with your doctor regarding any is imperative.
Additionally, some more common effects to taking Provigil are anxiety and nervousness. Some lesser common effects are back pain, burping, reduced appetite, diarrhea, constipation, mouth dryness, skin dryness, feeling of constant movement of self, feeling constant moving of surroundings, redness of the skin, heartburn indigestion, stiff muscles, sores, ulcers, or white spots on the lips, in the mouth, sour stomach discomfort upset stomach, or stomach pain, runny nose or stuffy nose, swelling tingling, burning sensations, prickly sensations of the skin, and/or vomiting.
Research has also unexpectedly shown that Modafinil leads to enhanced sensory perceptions. Athletes have found that it helps them with hand-eye coordination and reaction time. This is possibly due to quicker reflexes and faster visual processing.
Individuals will find that their vision and their sense of touch are effected for the most part. Also, research shows that it enhances the auditory sensations; in fact, when you are listening to music. As far as sight is concerned, Modafinil may make lights and colors seem vividly brighter which can allow the individual see more in detailed.
When the American Academy of Sleep Medicine released a statement on the off-label use of Provigil, this is what the statement said: “Provigil should be used only under the supervision of a doctor for the treatment of excessive sleepiness caused by narcolepsy, obstructive sleep apnea or shift work disorder.”
Provigil or not?
In conclusion, the reports of serious dermatologic adverse effects may result in some people not wanting to use Provigil; also, psychiatric events in some people has resulted in the FDA’s Pediatric Advisory Committee to reject in using it for children. Hence, the research given has unanimously recommended that warning labels should be given against prescribing it to children. For instance, usage of first and second-line treatments have been researched and found that those have failed in children’s use.
Nevertheless, the benefits outweigh the risks of using Provigil for adults, though. Using Provigil may benefit some individuals, but for the most part, those with the sleep disorders, such as sleep apnea and those with attention deficit hyperactivity disorder, and fatigue, may benefit more so. Finally, speaking to a physician about the use of Modafinil such as Provigil would be a wise decision overall.