Provigil in the UK

Provigil UK

What is This?

Modafinil, also known as Provigil in the United States of America, is a nootropic stimulant that is used for promoting wakefulness in patients who suffer from sleep disorders such as narcolepsy, obstructive sleep apnea, and shift work sleep disorder. Additionally, the medication can also be used for other conditions, which can only be determined by a licensed physician. The way that Modafinil works is practically unknown; however, it is described as a “wakefulness-promoting agent” that alters neurotransmitters that are located in the human brain.

 

Benefits

There are some benefits of Modafinil that are essentially very appealing. Some of these benefits include and increased amount of energy and more alertness, especially for those individuals who suffer from various forms of sleep disorders. Another great benefit to using Modafinil is that it provides a significant boost to mental energy, which is something that not a lot of other stimulant-based medication such as Ritalin and Adderall can do. Additionally, this medication also does not provide side effects such as nervousness or jitteriness.

 

Another great benefit of Modafinil is that it also siginificantly reduces the amount of drowsiness and fatigue that a patient who takes it can feel. As a result, this can lead to a person becoming much more productive, motivated, and driven.

 

Another great, yet rather unexpected, effect of Modafinil is that the medication can lead to enhanced sensory perceptions, which can be extremely pleasurable whenever it is approached with the right frame of mind, especially in terms of both touch, sight, and hand-eye coordination.

 

Dosage

Typically, the dosage amount of Modafinil depends on the particular sleep disorder that it is being taken for. Here are some examples:

 

*If Modafinil is being taken for narcolepsy, doctors recommend that 200mg of Modafinil be taken orally every morning.

*If Modafinil is being taken for obstructive sleep apnea, doctors recommend that 200mg of Modafinil be taken orally every morning.

*If Modafinil is being taken for shift work sleep disorder, doctors recommend that 200mg of Modafinil be taken orally one hour before starting your shift at work.

*Modafinil is not approved by the Food and Drug Administration for pediatric attention deficit disorder.

 

Side Effects

As with all other drugs, there are many different side effects that can come as a result of taking Modafinil. Some of these side effects are more common, while some are less common. Additionally, there are other side effects that can arise as the result of an overdose of the medication. These side effects are as follows:

 

*More Common Side Effects: anxiety, nausea, headache, nervousness

 

*Less Common Side Effects: diarrhea, heartburn, dry mouth, bowel movement difficulty, appetite suppression, upset stomach, vomiting, runny nose, sore throat, shortness of breath, confusion, dizziness/fainting, trembling/shaking, difficulty urinating, chest pains, stumbling, memory issues, chills/fever, increased thirst, mood change, unusual bruising/bleeding, tarred/black stools, dry skin, back pain

 

*Side Effects Due to Overdose: Excitement/agitation, increased blood pressure, difficulty sleeping, increased heartbeat

 

Effects

As previously stated, Modafinil offer many different effects, with the most popular being that it greatly assists individuals obtain a better sleep cycle by combating issues relating to sleep disorders such as narcolepsy and obstructive sleep apnea. Issues such as this can seriously affect the cognitive function of these individuals throughout the daytime hours.

 

Uses

As with any other medication, Modafinil is something that should always be taken as prescribed by your doctor and should never be taken in amount larger or smaller than directed. Typically, this is a medication that is taken during the morning hours to prevent patients from falling asleep during the day. Additionally, those who suffer from conditions such as shift work sleep disorder typically take Modafinil one hour prior to the beginning of their shift in order to help treat this condition.

 

Modafinil is prescribed in increments of 12 weeks or less and may also be taken with or without food, whichever the patient prefers.

 

Patients who suffer from conditions such as obstructive sleep apnea may also be prescribed a CPAP machine alone with their prescription of Modafinil. This is a machine that should always be used in conjunction with this medication until your doctor directs you to stop using it.

 

If, while taking Modafinil, you continue to experience an excessive amount of sleepiness, you are advised to contact your doctor as soon as possible.

 

Long-Term Use

Overall, the exact long-term effects of Modafinil are currently unknown, which has led to the United States government to classify the drug as a Schedule IV controlled substance. This means that Modafinil has the risk, albeit low, of being potentially abused and, therefore, cannot be legally obtained without a prescription from a licensed physician.

 

Previously, it had been stated that one long-term effect of the medication was that it worked to enhance cognition; however, this has not been officially confirmed in any way. As of right now, again, there seems to be no official information regarding positive long-term benefits of Modafinil.

 

Research

Here are some additional facts regarding Modafinil:

 

*This medication should not be taken if you are someone who has ever had an allergic reaction to either it or Armodafinil, also known as Nuvigil.

 

*If you are someone who is either pregnant or planning to become pregnant, consult your doctor prior to taking Modafinil, as there is currently no evidence regarding whether or not this medication will cause any harm to an unborn baby.

 

*If you are someone who takes birth control, taking Modafinil can make that less effective.

 

*Modafinil is not approved for anyone who is younger than 17 years of age.

 

*If you are breastfeeding, consult your doctor prior to taking Modafinil, as it is unknown whether or not the medication can either pass into breast milk or harm a baby.

 

Final Thoughts

If you are an individual who suffers from any kind of sleep disorder and are looking for an effective form of medication to combat those issues, then Modafinil may be exactly what you’re looking for. However, as previously mentioned, the government has officially classified this drug as a Schedule IV controlled substance, so if you end up taking it, you will need to be extremely careful when doing so, especially thanks to the many different side effects that can present themselves. And because Modafinil is a Schedule IV substance, this means that you definitely won’t be able to obtain it as easily as you might think you will. Either way, Modafinil is something that you should consider only if you seriously need it…not just if you want it as a quick fix.

Modafinil Anxiety

What is this
Provigil is a medication that promotes wakefulness. The drug is thought to work by altering the natural chemicals known as neurotransmitters in the brain. It used to treat excessive sleepiness that is caused by sleep apnea, narcolepsy or shift work sleep disorder.
It is also a prescription medicine for narcoleptics that increases alertness and prevents sleep. It enhances cognition and memory and is a potent and highly regarded supplement in the group of nootropics. A typical dose of this drug will last around ten to twelve hours and as such it needs to be taken at an appropriate time of the day to prevent any interference with sleeping patterns. This drug is popular with those studying or working in academic areas as well as professional who requires consistently alertness during their working hours.
Benefits
If you take this drug at the recommended dosage, you will be able to enjoy these benefits;
– Reduced stress and anxiety
– Makes one stay awake and active
– Sharpens mental clarity hence helping one when making decisions
– Improvement of short and long-term memory
– Boost of new task learning and memory attention
– Safely increased focus, energy, and mental performance
Dosage
Provigil is usually taken each morning to prevent daytime sleepiness or one hour before the start of a work shift to treat work-time sleep disorder. Users can take the tablet with or without food, and it is usually taken for twelve weeks or less.
The recommended dosage for an adult suffering from narcolepsy is 200mg orally in the morning and adults suffering from Hypopnea syndrome is 200mg orally in the morning. For night work sleep disorder, the drug should be taken one hour before the start of the work shift and the dose is also 200mg. if you missed a dose, you should never take an extra medicine to make up the missed dose.
This medicine may impair the thinking or reactions, and so users should be careful if they drive or do anything that needs them to be alert. Also, you should avoid other dangerous activities until you know how the drug will affect your level of wakefulness. Users should also avoid drinking alcohol while taking the medication.
Due to the potential adverse reactions, Provigil is not necessarily suitable for everyone. Individual with underlying health issues may exacerbate their condition especially should it be and circulatory or organ concern. People with a history of dependency are often advised to steer clear. Drugs and alcohol ought to be avoided unless approved by a healthcare professional.
Side effects
Provigil is considered to be safe without dangerous side effects when used as prescribed. There are some mild Provigil side effects that you may encounter during normal use. Some of the potential adverse effects that can be caused by this drug are;
– Skin rash, blisters or peeling
– Mouth sores, trouble swallowing
– Fever, shortness of breath
– Swelling of legs
– Dark urine and jaundice
– Bulging of the face, eyes, tongue, lips and throat
– Depression, suicidal thoughts or actions, and anxiety
– Hallucinations, aggression, being more active or talkative than usual and unusual thoughts and behavior
– Chest pain, uneven heart beats, and trouble breathing
– Skin rash, back pain, headache, and dizziness
– Insomnia, nausea, upset stomach and diarrhea
Effects
Taking Provigil raises histamine and locomotor activity in the central nervous system. The drug’s effects are shown to wear off once a potent inhibitor has depleted the natural neuronal histamine concentration. Several studies have discovered that the drug works by altering the CNS levels of histamine in the human body.
It can help individual function during the day as an alertness agent; it is also helpful in healthy people who are engaged in shift work and have irregular schedules.
Uses
Provigil has multiple uses, and some of these uses are;
– Used to stay awake during work hours if you have a work schedule that keeps you from having a regular sleep routine
– Used to reduce extreme sleepiness due to narcolepsy and other sleep disorders
– Used to increase acetylcholine and BDNF levels
– Improves cerebral circulation and neuroplasticity
– Promotes long-term and short-term memory formation
This drug is popularly used in college, campuses and in high-stress professions that need exacting attention to detail like finance, programming, and writing. The drug provides hours of unshakable concentration upon tasks and learning with few downsides.
Long-term use
There is no doubt that this drug can seriously enhance user’s ability to learn and perform over the long-term, but it requires to be respected with regards to the potential side-effects that may come with it. While there’s no medical classification for Provigil withdrawal, it’s likely that long-term users will feel a little sluggish once they finish taking Provigil.
Research
Some studies have shown that Provigil also known as Modafinil seems to be able to interact with a multitude of stimulatory systems including noradrenergic, serotonergic, glutaminergic, dopaminergic, histaminergic and orexinergic pathways. If a healthy person takes the recommended dosage of this drug two hours before cognitive testing, can improve working memory, visuospatial planning and reaction time. The drug was found to improve cognition, task enjoyment, planning and working memory. Due to the inability for Provigil to activate neuronal pathways involved in addiction, it is thought to have a low abuse potential about other supplements.
Final thoughts
It may be best to reflect Provigil as a father figure when it comes to procuring study and work performance aids that are potent enough to be effective yet safe enough to justify consistent use. This drug is a comparable substance that can be purchased and owned legally so would be the root to go for not unless of course you’re legally entitled to a prescription for Provigil and, in that case, it’s the best option out there.

Modvigil Benefits

Modvigil Benefits

Modafinil is the generic version of Provigil. Doctors use it to promote wakefulness in patients with sleep disorders, such as narcolepsy. It is also used for patients with shift work sleep disorder, and excessive daytime sleepiness that is associated with obstructive sleep apnea. It also has widespread off label use as a cognitive enhancing agent.

Benefits of Modafinil

The main benefit of Modafinil is that it helps to keep patients awake. This is not just for patients with narcolepsy. It can also be very beneficial to patients who suffer from diseases such as Multiple Sclerosis, which causes patients to feel fatigued very often. Patients who suffer from certain cognitive disorders can also benefit from the use of Modafinil. One of the most common cognitive disorders that doctors prescribe this medication for is adult ADD and ADHD. It is also beneficial for patients with acute liver failure and geriatric patients.

Dosage

The recommended dosage for Modafinil depends on the condition that is is being prescribed for.

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Narcolepsy and Obstructive Sleep Apnea (OSA): patients with these types of disorders should take 200 milligrams in the morning, orally. Doses up to 400 milligrams can be given in a single dose and can be tolerated, however, there is no evidence that the additional 200 milligrams have any additional benefits.

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Shift Work Disorder (SWD): The recommended dosage for patients with this disorder is 200 milligrams taken orally as a single dose. It should be taken an hour before the patient starts their work shift.

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Severe Hepatic Impairment: Patients with severe hepatic impairment should take half of the normal dose, 100 milligrams.

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Geriatric patients: Geriatric patients should take lower doses, and they should be monitored consistently.

Side Effects of Modafinil

Some patients who have taken Modafinil has reported certain side effects. Some of the more common side effects include:

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tyrosineHeadache

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Nausea

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Anxiety

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Nervousness

There are also some less common side effects. These include:

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Decrease in appetite

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Back pain

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Diarrhea

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Belching

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Dry mouth

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Dry skin

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Constipation

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Flushing or redness of the skin

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Muscle stiffness

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Heartburn

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Indigestion

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Ulcers, sores, or white spot in the mouth or lips

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Upset stomach

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Stuffy nose

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Runny nose

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Stomach discomfort or pain

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Vomiting

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Tingling, burning, or prickling skin sensations

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Swelling

Interactions

It is important that patients know what foods and drug will create an adverse reaction if they are consumed with Modafinil.

Drug Interactions:

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Abilify

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Adderall

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Aspirin

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Crestor

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Cymbalta

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Fish Oil

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Lamictal

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Lexapro

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yrica

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Nexium

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ProAir

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Prozac

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Topamax

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Xanex

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Zyrtec

Long Term Use of Modafinil

There are no physical dangers of taking Modafinil for a long time. However, it is very easy to stay awake when you are taking Modafinil. This can make it very easy to stay up late, which over time can lead to sleep deprivation.

Modafinil Abuse

Because Modafinil does not produce a feeling of euphoria, it is not often abused. It can, however, be overused. Students who are struggling to stay awake for exams will often purchase the drug on the street, and take more than the recommended dosage while cramming for their exams.

Modafinil Research

Many doctors are researching ways that Modafinil can help with other conditions.

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Depersonalizatin disorder: When used alone, Modafinil has been reported to be effective with some people with this disorder. The people most likely to respond are those who have attentional impairments, hypersommia, and under arousal.

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Psychiatric/neurodegenerative disorders: Modafinil is not approved for certain conditions, but can be helpful in the treatment of depression, bipolar depression, opiate dependence, Parkinson’s disease, schizophrenia, and disease related fatigue.

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Cocaine addiction: This drug is under investigation as a possible treatment for cocaine addiction. One of the main reasons is that the effects of Modafinil are opposite of the symptoms of cocaine withdrawal.

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Weight loss: One common side effect of Modafinil is loss of appetite. Therefore, studies have been done to determine whether or not this drug should be taken by obese patients to help them lose weight. According to a 2008 study, individuals who were taking the drug for shift work disorder, had an 18 percent decrease in their caloric intake.

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Post-chemotherapy cognitive impairment: Doctors are doing off-label trials with people who have post-chemotherapy cognitive impairment, also known as chemobrain, however, in 2011 it was found to be no better than the placebo.

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Motion sickness: Modafinil is not effective in treating motion sickness alone, however, when used along with scopolamine, it helps to reduce the drowsiness associated with scopolamine.

Legal Status

In the United States, Modafinil is classified as a Schedule IV controlled substance. It is illegal for anyone to use this drug unless they have a valid prescription from a licensed medical doctor. Even if students are taking the drug to stay awake, without a prescription, they can be arrested. There are a few countries that do not classify this as a controlled substance. These countries include:

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Canada (Schedule F Drug)

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Mexico

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United Kingdom (Possession is not illegal, but a prescription is required to get the drug)

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Australia (Schedule 4 prescription drug)

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Germany (In 2008, the drug was changed from a controlled substance to a prescription drug)

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India

Modafinil is an excellent drug for many reasons. First, it can treat disorders that can be debilitating for many people. Second, it can treat these conditions with very minor side effects. Finally, this drug is not often abused due to the fact that there is no feeling of euphoria. When patients suddenly stop taking this medication, there are often no withdrawal symptoms. Overall, it is a very safe and effective drug.

Modalert Dosage

What Is This?

 

A drug who’s most sought after effects tend to revolve around its ability to promote a sense of wakefulness, modafinil has use both in the medical community as a medication and outside of doctor supervision as a nootropic – or smart drug. It’s come under several different brand names in the past, but is most recognized by smart drug users as modafinil, its generic name.

 

Benefits

 

Modafinil’s benefits vary greatly and are almost entirely dependent on two things – whether or not the user in question responds to the drug, and what state the user is currently in. For the individual who is currently wide awake and full of energy, modafinil may have no more effect than a up of coffee. For those in a state of sleep deprivation; however, the drug can be an excellent way to bring the user back to a normal state of energy and well-being despite poor sleeping patterns. Modafinil is most beneficial to those in need of completing mentally intensive work (schoolwork, programming, etc.) who were unable to get the sleep they needed the night before.

 

Dosage

 

While everyone responds differently to different doses of the drug, Provigil – a brand name of modafinil – is often given at 200mg daily dosages. While some may find themselves in need of up to 400mg, it’s generally recommended one starts off between 100mg to 200mg merely as a means of testing the waters before jumping into moderate to high doses of a new drug. It’s never recommended to exceed 400mg; an already high dosage.

 

Side Effects

 

While to a lesser degree than many other stimulants, modafinil can carry typical stimulant-related side effects such as insomnia (especially when the drug is taken close to bed time), jitters, restlessness, headaches and anxiety. While the drug is unlikely to cause the average user these side effects on its own, the risk increases as the dose goes up. This is also true of mixing modafinil with stimulants such as caffeine or amphetamines. While addictive behaviors attributed to the use of modafinil are extremely rare, psychological tolerance may build up after long periods of frequent use.

 

Effects

 

Modafini’s effects are similar to stimulants such as caffeine and amphetamine, though likely with a lower occurrence of side effects. The effects are typically said to molecularbe more subtle than that of the above stimulants, providing less of a “buzz” in favor of giving the user the mental energy they need to perform certain tasks. No more, no less. These effects are typically felt more dramatically when taken by a user who is low in energy at the time, while those with a high level of energy may feel but a small increase to what they already have. The best Modalert dose is the one that fits each person best.

 

Uses

 

Due to its effects on the sleep-deprived brain, modafinil is commonly used to treat occasional bouts of sleep deprivation when an individual is expected to perform complex mental tasks despite their quality of sleep the night before. It may also be used as a general stimulant in place of – or in conjunction with – caffeine or amphetamines (though mixing stimulants is typically not advised).

 

Some folks find modafinil beneficial to use when completing mental tasks even when their energy is already at a level the user would describe as “normal.” While the difference in cognition, motivation and energy may not be as pronounced when used by such people, the difference is still noticeable and is still likely to increase one’s ability to check off lists or perform in a more optimal fashion when coding, engineering or engaging in similar practices.

 

While not traditionally used (or always necessarily recommended) as a means of curbing addiction, those who are less prone to side effects from modafinil than other stimulants may choose to permanently curb their addiction to coffee, tea, amphetamines or a multitude of illicit stimulants with the use of modafinil as a replacement therapy of sorts. Before taking on such a life-changing task through the use of drugs, it is extremely advisable to first consult with a doctor.

 

Long-Term Use

 

Aside from the occasional bout of side effects experienced by some users, modafinil has one large, potential deal-breaking setback – its effectiveness in long term use. For some (though certainly not all) users of the drug, tolerance may develop, requiring the user to need more of the drug to achieve the same effects, or even having one reach a point where not enough can be taken to recreate the effects one initially experience through the use of the drug.

 

Luckily, unlike the majority of stimulants, tolerance and addiction don’t usually go hand in hand when it comes to long-term use of modafinil. While it may be harder to achieve the same effects after a month of using the drug every day, users will often take a “tolerance break,” allowing the body to once again respond normally to the drug. To avoid the issue altogether, it’s recommended to keep use at under four days a week.

 

Research

 

Before beginning the use of any drug, no matter how benign, the smartest thing to do is gather as much information as you can regarding the drug itself as well as your own body chemistry and how that may affect your experience. The following sources are a great place to start:

 

Erowid’s modafinil vault – https://www.erowid.org/smarts/modafinil/

Your doctor (very important)

Wikipedia’s modafinil page – https://en.wikipedia.org/wiki/Modafinil

 

Final Thoughts

 

Compared to your typical smart drug, the potential means by which modafinil can be used successfully are huge. Addiction, low motivation, sleep deprivation and low cognitive function are all issue which people everywhere have been able to treat with the use of this drug. It certainly has its place among the ranks of the best nootropics and stimulants alike.

Modafinil in College

Modafinil in College

There is a nootropic drug on the market that offers a wide range of benefits for people who experience fatigue during their normal waking hours. Modafinil is a smart drug that offers multiple benefits with increased alertness and enhancement of the waking state. It helps in shaking the feelings of sluggishness and the inability to focus on daily tasks.

What is this?

Modafinil is also known as Provigil, its brand name. It is a popular smart drug that is currently used by prescription in Australia for the treatment of fatigue caused by narcolepsy and other disorders. It can be purchased online from a variety of vendors, but care must be taken to avoid fakes that may not deliver the same benefits as the genuine formulation. This drug is widely used to stimulate alertness and decrease fatigue.

Benefits

Modafinil aids in promoting wakefulness and alertness, but these are just a few of the benefits. It also features a nootropic effect for improving focus, concentration and recall. People who experience congnitive decline or deficiencies due to accidents or illness may benefit from its use. Those who suffer from sleep deprivation may get the needed boost to help complete daily tasks more productively and with higher energy levels without feeling tired or sluggish.

Cognitive enhancement is not the only benefit associated with the use of Modafinil. It is also known to help suppress appetite for increased weight loss. This adds an additional benefit for users who are trying to shed a few extra pounds, or for those who choose to use it as a part of their weight loss regimen.

Dosage

Modafinil may be taken in a range of dosages between 100 mg and 400 mg daily. It is best to begin with the lowest dosage to find out how your body will react to this smart drug, then increase the dosage until you get the effect that is desired. It is not recommended to exceed 400 mg daily as it will increase the likelihood of adverse side effects and in addition, will build a tolerance more quickly. Doses may be devided into two equal parts if desired or taken as a single dose. The half life of 12 hours should be observed and Modafinil should not be taken within 12 hours of the expected bedtime as it could result in insomnia.

Side effects

tyrosineThe most common side effects which have been reported with the use of Modafinil is headache. A smaller number of users experienced stomach issues, nausea, diarrhea, nervousness, dizziness and insomnia. In some cases, higher dosages may cause these adverse side affects or cause them to worsen.

Effects

Modafinil provides the effect of increasing wakefulness and alertness for periods of up to 12 hours. This is one of the reasons why it is important to take at least 12 hours before expected sleep time. Additional effects include nootropic benefits such as enhanced cognition for studying, retaining facts, focus, concentration and recall. Productivity is increased and fatigue is decreased.

Uses

Modafinil is used for many different purposes. Students and business people use it to sharpen thinking, logical reasoning and response time. It also makes studying come easier for many people. It is commonly prescribed in Australia for battling fatigue in people with health conditions such as narcolepsy and other sleeping disorders. Shift workers use it to shake off the feeling of sleepiness as they adjust to changing working and sleeping schedules.

Long-term use

This drug should not be used for extended periods without giving the body a break in between cycles. This is because tolerance is easily built, rendering the dosages less effective for providing the desired results. It is recommended that Modafinil should be used in conjunction and alternated with other nootropics that provide similar effects. Increasing dosages beyond the recommended limit of 400 mg per day may have consequences or cause an increase of unpleasant side effects.

Research

Clinical trials for the smart drug Modafinil have shown that it has the potential for a great many uses in alleviating fuzzy thinking and fatigue. Current research is being conducted to assess its usefulness for patients with ADHD. Control groups were used to determine the benefits of Modafinil with regard to cognitive enhancement with different dosages. There is still much more to be discovered about the mechanisms by which Modafinil works in the brain to deliver the results that have been observed. It is believed that it blocks the delivery of dopamine and also affects histamine within the physical constructs of the brain, altering body chemistry, but there is no concrete evidence to map precisely how this occurs. Further research is ongoing in order to pinpoint how it works and to provide support for extended use of this drug.

Final thoughts

Modafinil has multiple beneficial uses for combatting fatigue and increasing mental sharpness when taken at the recommended doses. The studies have shown that it is effective in stimulating key parts of the brain for increasing productivity and clearer thinking. The side effects for this drug are generally mild, but can become problematic for some users. The majority of people who responded to their experiences with modafinil give it a thumbs up for being effective and beneficial for relieving fatigue and enhancing congnitive functioning. There is the possibility of drug interaction issues if Modafinil is taken with certain prescription drugs. Anyone who is currently under a doctor’s care and taking prescription medications or supplements should consult with their physician before starting Modafinil.

 

What is Provigil?

What is Provigil?

What is it?

Modafinil is a drug that is marketed as an agent to improve alertness and wakefulness. It is indicated for people who suffer from excessive sleepiness due to conditions such as narcolepsy (Sleep walking), obstructive sleep apnea or work shift sleep disorder.

 

It is marketed under the trade name of Provigil in United states. It is classified as a scheduled drug by the US FDA and is restricted in its availability. However, in many other countries, Modafinil is a prescription drug but is not restricted in its availability.

 

One of the most common off-label use of the drug is as cognition enhancer. When administered, the drug is supposed to increase awareness and hence it is sometimes marketed as a nootropic agent.

 

How does it work?

The precise mechanism by which the drug acts is still largely unknown. However, tyrosinerecent studies have shown that the drug acts to increase the levels of a chemical substance (neurotransmitter) called Dopamine in the brain.

 

Dopamine is a neurotransmitter that is associated with increased alertness and enhancing the mood. It is also associated with the pleasure pathways of the brain. Modafinil causes an increase in the presence of Dopamine by blocking its uptake back in to the neurons. However, there are possibly many other mechanisms of action that can be attributed to the drug. The mechanisms leading to the improved memory and cognition are not completely clear as of yet.

 

 

What are the benefits of Modafinil?

Modafinil is an excellent drug for treating disorders such as excessive sleepiness. The drug belongs to a category of drugs called Euggeroic drugs that promote wakefulness. Medically, the drug has been used to treat many sleep disorders causing excessive daytime drowsiness and sleepiness.

 

Modafinil has also found some potential off-label benefits apart from promoting wakefulness. It has been successfully used in patients suffering from Multiple Sclerosis (MS) to reduce the neurological fatigue associate with the disease.

 

Apart from MS, it has also been successfully used to treat fatigue in a number of conditions including cerebral palsy, fibromyalgia and chronic fatigue syndrome.

 

As Modafinil promotes wakefulness, the militaries of many countries are interested investing the drug as an alternative to potentially dangerous and addictive Amphetamines. Many military outfits including French, British and US have been using the drug in certain missions requiring increased wakefulness and alertness.

 

It has also been used by astronauts in certain long term missions to combat fatigue and improve the sleep cycles.

 

What is the dosage?

The usual dosage of the drug is 200 mg once a day taken in the morning with breakfast. Although higher doses of up to 400 mg have been well tolerated but, they offer no additional benefit over and above the 200 mg per day dose.

 

What are the side effects of the drug?

Although Modafinil is well tolerated, certain side effects have reported. There are some serious adverse reactions reported in some individuals on Modafinil. These include:

 

l Serious rash

l Nausea

l Multi organ hypersensitivity reactions

l Persistent sleepiness

l Cardiovascular events

Some psychiatric side effects following the use of the drug have also been reported. These include mania, confusion, hallucination and in some cases even suicidal tendencies. These effects are more common in people having a history os depression or psychoses.

 

Modafinil has also been shown to interact with hormonal contraceptives reducing their effectiveness. The effects can last unto a month after stopping the dosage of modafinil.

 

Although the addiction potential of Modafinil is very low, it is still restricted in availability s per the US FDA. One of the reasons being the similarities it shares with other stimulant drugs such as Amphetamines. It is also associated to elevating the mood and hence has a potential to be misused. As such, Modainil abuse does exist and people have been found to use the drug for recreation purposes. Psychological dependence is only found in some cases where there is a daily overdose of the drug.

 

Long term use of Modafinil

Although the long term safety and effectiveness studies on Modafinil are not available currently, it is generally reported to be a safe drug if taken at a proper dosage.

 

A number of large scale clinical studies have found that there is no tolerance developed to the drug even after three years of daily usage.

 

Overdosing on Modafinil is not life threatening, but may cause some unwanted side effects.

 

Research:

A number of clinical trials conducted in m,any countries have revealed that Modafinis does offer significant benefits in maintaining wakefulness and reducing fatigue. Modafinil has been found to be very useful in treating many conditions such as:

 

l ADHD

l Neurodegenerative disorders such as MS and Parkinson’s disease and Schizophrenia

l Hypersomnia: The drug is used to treat people who have the condition and is also reported to induce a healthy sleeping cycle following the use

l Cognitive enhancement: Extensive research in Modafinil’s ability to improve cognition and memory has revealed that the drug improves some working memory but the results are largely inconclusive about improvement in attention span improvement and spatial memory

 

 Final Thoughts:

Although modafinil is a good drug in treating sleep disorders, the effect in improving cognition is still debated heavily. It is a good agent for people suffering form excessive sleep during the day time but the jury is still out regarding other claims including improving memory.

 

A number of user reviews of the drug indicate that there is significant enhancement in working memory and cognition. The abuse potential is minimal and hence the drug shows promise. Only time will tell whether there are any long term effects of the drug.

Modafinil for Memory

Modafinil Memory Benefits

For those who suffer from a foggy brain due to lack of sleep there is a cure. The drug is called Modafinil, the generic version of Provigil, and was designed to boost both alertness and energy levels. It’s stable and doesn’t come with a crash following the boost unlike the drug caffeine, making it ideal for those that need to fit in a late night cram session or survive a shift-changing work schedule.

 

 

 

There are many uses for Modafinil however researchers are not entirely clear on how it works exactly. Patients taking the drug discovered the benefits were multiple in nature. Most take the medication to enhance memory and improve brain function while a select few seek the medicinal qualities of the product.

 

 

 

What Is This

 

Used originally in the 1970’s for treatment of narcolepsy, Modafinil is an analeptic drug that’s distributed by Cephalon Incorporated. This drug is also known as a “smart drug”, designed to improve the subject’s performance when he or she is suffering from fatigue from a lack of sleep. Modafinil is sold under several other names which include: Provigil, Alertec, Modiodal, Sun Pharma Modalert, and Modapro.

 

 

 

Benefits

 

One of the many benefits of Modafinil is that it has actually been shown to reduce and in some cases even eliminate the damaging effects of sleep deprivation. The drug has also been known to enhance concentration and short-term memory making it an ideal study aid enhancement for demanding college curricula. It has also been known to increase positive thoughts and can help reduce stress and anxiety.

 

 

 

In addition, Modafinil can increase caloric expenditure greatly and decrease appetite by up to 38% of total daily caloric intake of the patient which makes it a great solution for patients desiring weight loss.

 

 

 

Dosage

 

Recommended dosage levels for Modafinil are: 100mg, 200mg, and 400mg per day. Starting with the 200mg is always the best choice for this medication and should be taken once daily. This can be taken with or without food and is advised to be consumed in the morning hours for a max duration of coverage lasting 8-10 hours.

 

 

 

In some individuals it’s recommended to begin the drug at a 100mg dose in order to adjust to the side effects. Some patients are far more sensitive to side effects in medications than others.

 

 

 

Side Effects

 

Modafinil has a number of side effects that should be acknowledged before taking. These include: insomnia, an increase in weight loss, a reduction in appetite, headache, nervousness, hypertension, nausea, dry mouth, and an increase in tyrosinenervousness.

 

 

 

Effects

 

Regularly taking Modafinil increases raises histamine and locomotor activity in an individual’s Central Nervous System. Once a person’s natural level of concentration wears out, the drug becomes ineffective.

 

 

 

Although the full component of the main part of the drug hasn’t yet been completely studied and researched, studies indicate that it works by altering levels of histamine in the Central Nervous System.

 

 

 

In controlled studies involving mice, the drug entered the orexinergic system. Certain mice lacked the the proper neuron and the drug failed.

 

 

 

Modafinil is less effective when taken later in the day so it’s advised to be taken in the morning to gain the maximum benefits of the medication.

 

 

 

Uses

 

Modafinil has been used to treat ADHD, narcolepsy, an aid in weight loss, and as a “smart drug”. The drug has also been used to treat patients suffering from Parkinson’s, bi-polar disorder, depression, and schizophrenia.

 

 

 

Longterm Use

 

Patients that have consumed Modafinil over a period of several weeks did not exhibit any withdrawal symptoms.

 

 

 

Overall, patients suffering from narcolepsy greatly benefit from longterm use of Modafinil. The drug also greatly improves overall health.

 

 

 

Research

 

Studies have not yet determined how Modafinil works exactly but research has shown the drug is linked to controlling levels of histamines, orexins, and hypocretins. Modafinil increases alertness and awareness by stimulating a response in the histaminergic tuberomammillary neurons in the brain.

 

 

 

It is not an amphetamine and it doesn’t seem to cause addiction or withdrawal problems in patients. The drug also does not carry the risk of potential heart health issues found in that of Ritalin making it an ideal alternative for patients suffering from ADD or ADHD.

 

 

 

During the 9-week July 2000 clinical trials only 43 out of 341 patients quit taking Modafinil due to adverse reactions. About half of the total patients saw improvement in the treatment of narcolepsy symptoms alone.

 

 

 

Final Thoughts

 

Although the benefits are many, Modafinil has not been FDA approved and most doctors will not write an “off-label” prescription, making it difficult to gain access to this drug. Many individuals in the United States often purchase Modafinil from international venders that produce questionable quality versions of the drug. It is extremely dangerous to consume illegal versions of this drug for obvious reasons regarding potential health risks to the patient. Although it is slight, adverse reactions were recorded in the July 2000 9-week clinical studies and tampered versions of the medication could pose a much greater risk than the true version of the drug.

 

 

 

Those interested in purchasing Modafinil from international venders may do so online off of the “grey market”. Customers in the United States should note though that purchasing this drug from an international vender is legal but once the package enters United States territory possession of the pills then becomes illegal.

 

 

 

Modafinil is an exceptional memory enhancement drug that claims it does not pose any significant health risks and the data supports this. However, the decision to take the drug should be left to the individual wanting to try it as the access to it and the potential tainted versions created internationally are far more dangerous than the real medication itself.

 

Modafinil as a Nootropic

Modafinil as a Nootropic

Nootropic drugs are becoming more viable solutions for addressing problems with cognitive functioning. Modafinil, also known as Provigil is used for decreasing fatigue in people from all walks of life. This is the most common use, but research has shown that this smart drug is capable of providing users with many more benefits in addition

What is this

Modafinil is a nootropic drug that works in the brain to target selected areas that control cognition. It stimulates states of increased wakefulness and alertness, even when the subject may be tired from poor sleep or other medical conditions that induce fatigue. It is often prescribed my medical doctors for a variety of purposes, but can be purchased legally without a prescription. It works by inhibiting the delivery of dopamine in the brain, causing a stimulant effect.

Benefits

Modafinil makes users feel more alert and less sluggish. It increases productivity levels in many different situations. Studying is made easier because this drug enhances the ability to retain information that is read or heard, and it also improves concentration, focus and recall. This is also helpful for people who do public speaking for a living, for engineers who must focus on minute details and for those who must be at their mental best. Clearer and more accurate thinking processes with faster response time has also been reported as a benefit of Modafinil. Finally, it works as an appetite suppressant and helps to improve weight loss regimens.

Dosage

This drug may be taken once or twice per day. The maximum daily allowance ranges between 100 mg and 400 mg total per day. First time users should start with the lower dose until they know how their bodies will react to it. Do this for the first week and then gradually increase the dosage until the desired effects are achieved.

Side effects

There is a potential for side effects with the use of Modafinil. Not all users experience these. The most common is headache. Less commonly, some users reported dizziness, nausea, difficulty getting to sleep, diarrhea and stomach upset, molecularnervousness and anxiety. Some symptoms go away after the body has adjusted to the presence of the drug. Higher doses can cause side effects in some users. If this is the case, the dosage amount can be reduced. If the symptoms persist, discontinue use. There is also a high potential for tolerance building with Modafinil. This can cause it to be less effective in lower doses, but it is important to not exceed the 400 mg per day limit. Users who are under a doctor’s care and taking prescription medications or supplements should seek the advise of their doctors before taking Modafinil to ensure that no drug interactions may occur and that it does not worsen any existing health conditions.

Effects

Modafinil produces a stimulant effect within the brain. It helps to lessen fatigue and create a heightened state of wakefulness and alertness. Thinking processes have been reported to become faster and sharper with an increased ability to retain and recal information for better memory function.

Uses

This drug is used as both a prescription drug for treating cognitive and neurological disorders and their symptoms, and as a study aid for increasing mental acuity. Persons with sleeping disorders who have difficulty with sleepiness during waking hours may use Modafinil to increase alertness so their day will be more productive. Students find studying easier and more productive as well as professionals who have a need for clearer and faster thought processing. People with narcolepsy and shift workers who deal with constantly changing sleeping schedules find relieve from grogginess and fuzzy thinking with Modafinil.

Long-term use

Modafinil tolerance can be built easily in the system of the body making it less effective for long term use. It is recommended that Modafinil be used in cycles with other nootropic drugs that deliver similar effects to avoid this.

Research

Studies have shown that Modafinil has many different features that are valuable for the treatment of a broad scope of disorders and situations where mental functioning is imparied. It stimulates certain areas of the brain to bring clearer thinking, increased concentration and focus and the alleviation of tiredness. It is not a cure for any preexisting condition, but rather, aids in reducing the symptoms. Researchers have not yet discovered exactly how Modafinil works within the body. More is known about the results of use at certain dosages. There is current exploration underway to assess its value in the treatment of ADHD and similar neurological disorders, but more research is needed to provide concrete evidence of its effectiveness in this area.

Final thoughts

Modafinil is among the favored nootropic drugs for the treatment of conditions that cause fatigue during waking hours. Its clinical use in the treatment of medical conditions is expanding with the research that unearths new benefits for people from a variety of backgrounds and medical conditions. When taken at the recommended dosages, it is considered to be safe for human consumption. Some users experienced unpleasant side effects but the majority found the benefits to outweigh the potential for adverse reactions. As with any drug, it is important to consult with a trusted health care provider before starting a regimen of supplemental medications. This is to lessen the chances of interactions with other prescription medications or supplements that are being taken. The use of Modafinil with other nootropic drugs in an alternate cycling is safe and recommended to avoid tolerance building.

Provigil Dosing

Provigil Dosing

Are you in search of a treatment for chronic fatigue or fuzzy thinking? Modafinil is a powerful nootropic or smart drug that is effective for increasing alertness, wakefulness and decreasing fatigue in users. These are just a few of the benefits that have been reported by users and research analysts. The multiple effects produced by Modafinil make it a multifunctional drug that can be used to treat a variety of medical conditions.

What is this?

Modafinil is a formulation of compounds that work in the brain by blocking the transmission of dopamine. Although not yet completely understood, it affects certain areas of the brain and reduces fatigue and feelings of sluggishness. It is considered to be safe for human use when taken at the recommended dosages. Modafinil is obtained by physician prescription in some regions, but is available for online purchase in others.

Benefits

The benefits of Modafinil are clearer and faster thinking processes. It alleviates the discomfort of fatigue and provides a more wakeful and alert state of mind which allows users to become more productive without the misery of feeling tired while how to use adderallattending to required tasks. It allows for faster learning with greater recall and enhanced memory functioning for improved testing results in an educational environment. There is an added benefit of appetite suppression which makes Modafinil an asset for use in weight loss programs.

Dosage

The recommended dosage of Modafinil is between 100 and 400 mg per day. Starting with 100 mg allows you to find out how your body will respond to Modafinil before you make any increases. Some users are content with the lower doses while others may require more. Exceeding the maximum recommended dose is strongly discouraged because it carries with it the increased risk of adverse side effects and tolerance building, making it less effective. Modafinil may be used in conjunction with other nootropic drugs in a cycling regimen to help reduce tolerance.

Side effects

Not everyone who takes Modafinil experiences side effects. For those who do, the most frequently reported is headache. This may go away as the body makes adjustments. Less frequent reported side effects include nervousness, insomnia, dizziness, stomach upset, nausea and diarrhea. These, however are less common. There is a risk of drug interaction issues if taken with certain prescription or supplement medications. It is best to seek the advise of your doctor if you are currently taking any medications before you begin Modafinil.

Effects

Modafinil produces a stimulant effect that helps in making users feel more awake and more alert. Mental processes are improved for most and users have reported that their thinking is much clearer and more precise. They find it easier to study for exams because they retain information more easily and their memory allows for faster retrieval of the facts which have been studied.

Uses

Modafinil is commonly used as a prescription treatment for people who suffer from fatigue due to narcolepsy, from constantly changing sleep schedules due to shift work, or from other health conditions that cause fatigue and tiredness. It may also be purchased online for use as a smart drug to enhance cognitive functioning. It is used to help improve thinking and memory, heightening mental acuity.

Long-term use

Extended use for long periods of time is likely to result in tolerance building. When this occurs, the drug becomes less effective and higher doses are required to achieve the same results. Exceeding the recommended limit for dosing is strongly discouraged because of the potential for unwanted consequences. Modafinil may be cycled with other nootropics to avoid this dilemma.

Research

The current research shows that Modafinil is an effective treatment for the symptoms of tiredness, fatigue and some types of cognitive decline. It sharpens thinking ability and dissipates feelings of tiredness for a more productive and energetic approach to task completion. Exactly how it works within the body is still a mystery. All that is currently understood about the mechanisms of operation is that it seems to block dopamine transmission and affects specific areas of the brain responsible for producing a stimulant effect with increased cognition. Study participant reports confirm that this drug is highly effective for combatting fatigue and enhancing cognitive function on many different levels. The few drawbacks of Modafinil are that there is a potential for side effects in some individuals. It is also more difficult to find and more expensive than other nootropics in its class.

Final thoughts

Modafinil is a multifunctional compound that also features nootropic properties for increasing mental ability. Physicians recommend it for relieving fatigue caused by a number of different health related conditions. Although it is not a cure, nor is it a substitute for getting the proper amount of rest, it helps to better control the symptoms caused by these situations. When taken at the recommended dosages, Modafinil is considered to be safe for use by most people. Students, business professionals and persons who suffer from the symptoms of chronic medical conditions may benefit from the use of Modafinil. Those who are trying to lose weight can use it to help curb the appetite while reaping the benefits of the nootropic effects as well.

Side effects are possible as with nearly any drug or supplement, but are generally mild and tend to go away after a few days or with reduction of dosage amounts. For multiple benefits in alertness, wakefulness and improved thinking processes, Modafinil is the smart drug of choice for many satisfied users.

What are Nootropics?

What are Nootropics?

Nootropics Overview: Are Nootropics Really So Effective?

What is this?

The term “nootropics” was suggested to refer to the supplements that have specific activating effect on the integrative functions of the brain alongside with stimulating learning process, improving (reducing) memory and mental performance, enhancing brain resistance to aggressive influences and reinforcing the cortico-subcortical connections.

Benefits

First and foremost, nootropics don’t possess psychostimulant or sedation effects. In addition, they don’t cause specific changes in the bioelectric activity of the brain. However, they to a greater or lesser extent stimulate the transfer of excitation in central neurons, facilitate the transfer of information between the hemispheres of the brain, improve energy processes and brain blood flow and increase general resistance to hypoxia.

The most important manifestation of their action is the activation of intellectual and mnemonic functions. Sometimes, nootropics are effective just in combination with other stimulants. For instance, to improve physical performance, nootropics are only effective in combination with psychostimulants and actoprotectors.

Examples

The neuroprotective drugs are the agents of various pharmacological groups, which have a positive impact on the work of nerve cells and improve their structure.

  1. Substances stimulating the metabolic processes in nerve cells:

 

Pyrrolidone derivatives: Piracetam, pramiracetam, Fenilpiratsetam and others;

derivatives of gamma-aminobutyric acid (GABA): Aminalon, Pikamilon, hopantenic acid, Phenibut; pantothenic acid derivatives: Pantogam; derivatives of vitamin B6 – pyridoxine: Pyritinol; products containing DMAE: Lucidril, Tsentrofenoksin; preparations containing peptides: glycine, Cere, Aktovegin; antihypoxants vitamins; vitamin-like, general tonic ingredients: vitamin B15, vitamin E, folic acid, succinic acid, ginseng and other extracts.

 

  1. Substances having a positive effect on blood vessels, or vasotropic supplements:

 

Ksantinol nicotinate;

Vinpocetine; Pentoxifylline; Cinnarizine; Instenon.

 

  1. Drugs stimulating memory and learning processes:

 

 

cholinomimetics and anticholinesterases: Galantamine, Choline, Amiridin and others; hormones: corticotropin adrenocorticotropic hormone; endorphins, enkephalins.

Research

In this paragraph, we are going to name the processes that lie in the foundation of nootropics activity:

l Activation of plastic processes in the central nervous system by enhancing the synthesis of RNA and proteins;

l intensification of energy processes in neurons;

l activation of the processes of transmission of nerve impulses in the central nervous system;

l optimization of polysaccharides, particularly glucose;

l inhibition of the formation of free radicals in the cells;

l reduction in the need for oxygen in hypoxic conditions;

l membrane stabilizing effect (regulate the synthesis of proteins and phospholipids in nerve cells, stabilizing the structure of cell membranes).

img3Dosage

There are two main ways of taking the pills: orally or parenterally (intramuscularly or intravenously). The doctors recommend taking the pills after the meals.

The dosage and the duration of treatment are determined individually, depending on the disease and the characteristics of his clinical course.

For instance, the average dosage of Paracetamol is one pill two times a day. The effect is noticeable immediately, but the long-lasting results come only after 4-8 weeks of regular treatment.

Side effects

Nootropics rarely cause any side effects, but in some patients they may lead to the following adverse reactions:

l headache,

l irritability,

l anxiety,

l sleep disorders,

l drowsiness;

l Blood pressure drops;

l rarely, in elderly patients, – increased symptoms of coronary insufficiency;

l nausea,

l stomach discomfort, diarrhea, or constipation;

l strengthening of psychopathology;

l allergic reactions.

Long-term use

The specialists have various opinions about the long-term usage of nootropics. One says that the patient can take the course of supplements not more than 3 months, then make a break for 2 months and repeat the course again. The others claim that one can harmlessly take the supplements for 6 months. Anyway, it is better to consult the specialist before making any final decision.

Final thoughts

In conclusion, the pills invented for the patients are continually transforming into a trendy dope for workaholics. For example, nootropics drugs, which in the 70s were created for the treatment of senile dementia, Alzheimer’s disease, narcolepsy (irresistible bouts of sleepiness), and attention deficit disorder, are now positioned as a means of increasing efficiency.

Keep in mind that the information provided in this article is not a guide to action: in the case with any unpleasant symptoms one should not self-medicate. You are recommended to ask for professional help and consult an experienced specialist.