Modafinil in Australia, Legal Status and Where to Buy

Modafinil in Australia, Legal Status, Dosage and Where to Buy

In Australia, Modafinil is a prescription used to treat Narcolepsy, COPD, ADHD, Fatigue and Shift-Worker sleep disorder. One of it’s main uses overseas in Australia however, is for recreational use, as a “Smart Drug” or cognitive enhancer. In recent years, shortly after the production of popular Smart Drugs and nootropics movies like “Limitless” and “Lucy,” as well as the newfound “Limitless TV Series,” Provigil has gained mainstream popularity as a powerful Smart Drug across the globe. This article will look at how the drug is used more specifically in Australia.

Modafinil Popularity in Australia

Let’s look at the numbers. As of late, there are currently over 1,000,000 people in Australia that take Modafinil (that are prescribed it), and that’s just on record. Most users who take it take it for narcolepsy, fatigue, etc. yet a huge number of these prescriptions are also written for ADHD and Shift-Worker sleep disorders, which are a bit more subjective with Modafinil in Australiaregards to how much someone “needs” a drug like Modafinil. These two disorders make up almost half of the population of Provigil users in Australia, and it’s safe to say that if you’re getting your doctor to write you a Modafinil prescription for “worker shift sleep disorder” that you’re using the drug for cognitive performance enhancement. This “disorder” is basically a fancy medical way of saying that you work very irregular hours, and would like a powerful stimulant drug like Provigil to use so you can work an erratic schedule, whether it be flying around the world, staying up all night coding, or working the graveyard shift at a new job. Australians, just like the rest of the Modafinil population, are catching on to Modafinil’s effectiveness, and are taking advantage of loopholes in order to get their hands on the world’s first “real Smart Drug.”

See following article for more details: https://www.theguardian.com/science/2015/aug/20/narcolepsy-medication-modafinil-worlds-first-safe-smart-drug

Side Note*

Modafinil is also used for a host of legitimate reasons, including

ADHD

Fibromyalgia

Fatigue

Dystrophy

Cerebral Palsy

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This is not subjective of a full list of all issues Modafinil is prescribed for, off-label or otherwise.

What is Modafinil?

Modafinil is a prescription used for Narcolepsy and COPD, as well as ADHD-most commonly. It has also gone mainstream as a cognitive enhancer for a number of reasons. Modafinil does a number of things that one might look for in a cognitive enhancement drug. These include, increasing mental and physical energy levels, reducing fatigue, helping the user to focus better and have a better working memory, and aiding the individual in learning and productivity in whatever task the user may be engaged in. Modafinil is a drug for users who want to work hard and work hard for long periods of time!

Benefits

Because it acts on Primary excitation neurotransmitters, such as Dopamine, histamine and norepinephrine, the gist of Modafinil’s most powerful benefits are that it increases energy, productivity, mood, focus and motivation. It’s effects are not unlike that of an amphetamine, just cleaner, less addictive and with less risk and side effects.

Dosage

In-short, typical dosages of Modafinil are going to range from 100-400 milligrams per day. 200mg is the most common dosage (per day, once in the morning) 100mg is typically the minimum effective dosage, and 400mg per day serves as kind of a ceiling dosage (go any higher and side effects get worse and beneficial effects only improve marginally.)

Research on Modafinil

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2654794

https://examine.com/supplements/adrafinil/

http://www.studydrugs.net/Adrafinil-Review.html

https://www.drugs.com/provigil.html

Final Thoughts on Modafinil in Australia

Modafinil has become a force to be reckoned with in the US, overseas, and especially in Australia as a powerful cognitive enhancement drug that works. Get your hands on some Modafinil today and discover what you’re brain on Smart Drugs is capable of!

Sources: 

  1. https://clinicaltrials.gov/ct2/show/NCT02886130
  2. https://www.ncbi.nlm.nih.gov/pubmed/1662399
  3. https://www.ncbi.nlm.nih.gov/pubmed/1409797

*Disclaimer: Statements found within have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease. Always consult a physician if you are unsure about taking a new supplement. Do not take this supplement if you are under 18, if you are pregnant, nursing, or have any cardiovascular issues. Scientific studies cited are not conclusive and have limitations, due to of their closed environment nature. Referenced studies will not necessarily determine your experience with a supplement, since there are many unaccounted variables, which fall outside the scope of the studies. All refunds must be brought to our attention within 7 days of delivery in order to be considered for reimbursement

Piracetam vs Modafinil

Piracetam vs Modafinil

Piracetam and Modafinil are two very different nootropics, and while both are cognitive enhancers, act on entirely different areas of the brain to force their effect-with this in mind, comparing them should be quite interesting. Both have actually been deemed “the real Limitless pill” on loads of nootropics forums and Smart Drug blogs, and both are two of the most popular (probably THE most popular) nootropics currently on the market, they are also each effective in their own ways. This article will look at the pros and cons of each nootropic seperately, and then will make an educated comparison about the two drugs. Piracetam vs Modafinil is a very interesting and heated debate, and this article should serve to inform readers about what to look for in each of the two drugs.

What is Piracetam?

Piracetam is sometimes caPiracetam vs Modafinillled the “original nootropic drug,” and was one of the first Smart Drugs ever created. To give you the gist of how Piracetam works, there are loads of reviews about the drug saying that people don’t feel anything at all the first time you take it. Now compared to something like Modafinil, where reviews rave about the amazing energy, focus and euphoria that the drug gave, Piracetam is an entirely different game. Piracetam is a “cumulative type” nootropic, meaning that it can take a bit of time, usually 3-6 weeks of regular use, for the drug to build-up in your system before it has a pronounced effect on the user.

What is Modafinil?

Modafinil is much different than this, the first time you take Modafinil, you will absolutely feel something, and you’ll likely be surprised at how strong it is. There’s a lot of Smart Drugs on the web right now that are extremely overhyped, and Modafinil is not one of these at all (Piracetam might be, although there is definitely a time and a place for it depending on what you’re looking for in nootropics.) The first time you take Modafinil, it takes about an hour or so to kick in. Once it does, it lasts for 10-15 hours….I’ll repeat that, it lasts for 10-15 hours on a single dose! During this time span you can expect heightened focus, almost Limitless mental endurance, and a great boost in mood and working memory-this is a result of the dopamine,norepinephrine and histamine that are increased in the brain when using this drug. In-short, for the average nootropic user looking for a boost they can actually feel, Modafinil takes the cake over Piracetam by a significant margin.

For more research you can checkout these links:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2654794/

https://examine.com/supplements/adrafinil/

http://www.studydrugs.net/Adrafinil-Review.html

https://www.drugs.com/provigil.html

Dosage of Each

Dosage of Piracetam is 8-2400 milligrams 1-3 times daily, and you can go a lot higher if you so desire without risking any real side effects. Modafinil is a little tricker on dosing, go above 400mg and you’re in for some serious side effects. Modafinil dosages are usually 1-200 milligrams daily.

Side Effects

Side effects of Modafinil may include

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headache

dry mouth

increased thirst

insomnia

loss of appetite

Side effects of Piracetam can include

Headache

tiredness

jitters

insomnia

Increase in thirst

significant increase in appetite

anxiety

The two are very similar in side effects, and for the most part if you stick within normal dosing ranges and be sure to take Choline while using Piracetam, you should only experience mild side effects at worst for both of these nootropic drugs.

Long-Term Use, Piracetam vs Modafinil for Regular Use

To summarize it, you can use Piracetam on a more regular basis than Modafinil typically. For Modafinil, while it can be used regularly, it’s recommended you at least cycle off and take a holiday from the drug once in awhile.

Piracetam vs Modafinil, the Gist of these Two Popular Nootropic Drugs

So to put it quite simply, Modafinil is just the better Smart Drug when comparing Modafinil and Piracetam. Piracetam is subtle and weak and doesn’t always have effects for the user, whereas this is not Modafinil’s problem at all-Modafinil is a very strong stimulant nootropic and eugeroic, wakefulness-promoting drug, and you will have significant effects if you choose to take this supplement.

Sources: 

  1. https://clinicaltrials.gov/ct2/show/NCT02886130
  2. https://www.ncbi.nlm.nih.gov/pubmed/1662399
  3. https://www.ncbi.nlm.nih.gov/pubmed/1409797

*Disclaimer: Statements found within have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease. Always consult a physician if you are unsure about taking a new supplement. Do not take this supplement if you are under 18, if you are pregnant, nursing, or have any cardiovascular issues. Scientific studies cited are not conclusive and have limitations, due to of their closed environment nature. Referenced studies will not necessarily determine your experience with a supplement, since there are many unaccounted variables, which fall outside the scope of the studies. All refunds must be brought to our attention within 7 days of delivery in order to be considered for reimbursement

Modalert vs Provigil

Modalert vs Provigil for Total Cognitive Enhancement

 

Modafinil is one of the most commonly prescribed nootropic supplements on the market today, and it is sold under many different brand names. The brand names of Modafinil can Alertec, Modapro, Modiodal, Provigil, and Modalert. Some of these forms will differ somewhat in contents. Modalert has become popular among Modafinil fans because Provigil is so terribly expensive. Modalert is more generic, but many people say that it is just as effective.

 

What is it used for?

 

In many cases, people will just take supplements like Provigil and Modalert for the sake of cognitive enhancement and wakefulness. Many of the people who take these Modalert vs Provigilsupplements are not disabled in any way. However, this is also a set of supplements that can help the people who are suffering from various disabilities, including narcolepsy, shift work sleep disorders, ADHD and ADD, and sleep apnea disorder.

 

Benefits

 

Modalert can help people with their powers of concentration. Many people find that focusing on difficult tasks is much easier after they have taken Modalert. For the most part, people will specifically take Modalert for the sake of staying awake for a longer period of time. However, the supplement can be used to help people use their wakefulness wisely. They aren’t just going to be awake an uncomfortably and unproductively energetic. The people involved are going to be able to really use their newfound energy.

You can read these links for more research:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2654794/

https://examine.com/supplements/adrafinil/

http://www.studydrugs.net/Adrafinil-Review.html

https://www.drugs.com/provigil.html

Dosage

 

People will usually take Modalert for periods of twelve weeks at a time, at 200 mg a day. The people who are just taking the supplement for the sake of its stimulant and cognitive enhancement effects should limit themselves to taking Modalert when they really need it. People who are using the supplement for the sake of wakefulness should take it around an hour before they need to get down to business. This is a supplement that can last for around twelve hours, so it can certainly get people through an all-night study session.

 

Side effects

 

Many of the side effects of Modalert are the sorts of side effects that people will have to deal with when they take almost any supplement. For instance, nausea, headaches, and skin rashes are common. Insomnia is also common with drugs like this. Most of the more severe long-term side effects will only come from persistent use over the course of years, and not from the people who just take the supplement for the sake of giving themselves a boost.

 

Long-term use

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People who have kidney, liver, and heart disease in their families might want to be careful about taking Modalert long-term. This is a supplement that might raise a patient’s risk of getting liver disease. However, the risk of getting liver disease from Modalert is still lower than the risk of getting liver disease from alcohol consumption, and many people drink a lot of that as a matter of course. There is also a possibility that people can protect themselves from the long-term effects of sleep deprivation through the use of Modalert, which might also stave off cognitive decline.

 

Use in Silicon Valley

 

People in Silicon Valley will often work for days at a time on their software projects, knowing keenly that ninety percent of startups fail and that they need to be able to make the most of their time at the high-tech corporations. They also know that Modalert is one of the least expensive versions of Modafinil on the market, so Modalert is one of the drugs of choice for the people at Silicon Valley.

 

How to use properly

 

People should usually take Modalert an hour before they really need it if they are using it for the cognitive or stimulant benefits. The people who are using it to treat their sleeping disorders should take Modalert in the morning in order to get the benefits for most of the waking day.

 

Dangers

 

The risk of long-term liver and heart disease, as well as kidney disease, cannot be ignored by the people who are taking Modalert on a regular basis. As such, it is important for most people to take it only when they really need it, and not to take it like coffee.

 

Conclusion

 

Modalert is a solid supplement that will give people the benefits of Modafinil in a cheaper package than Provigil. They should be aware of the risks and rewards.

Sources: 

  1. https://clinicaltrials.gov/ct2/show/NCT02886130
  2. https://www.ncbi.nlm.nih.gov/pubmed/1662399
  3. https://www.ncbi.nlm.nih.gov/pubmed/1409797

*Disclaimer: Statements found within have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease. Always consult a physician if you are unsure about taking a new supplement. Do not take this supplement if you are under 18, if you are pregnant, nursing, or have any cardiovascular issues. Scientific studies cited are not conclusive and have limitations, due to of their closed environment nature. Referenced studies will not necessarily determine your experience with a supplement, since there are many unaccounted variables, which fall outside the scope of the studies. All refunds must be brought to our attention within 7 days of delivery in order to be considered for reimbursement

What is the Perfect Dosage of Provigil?

Provigil Dosage and Benefits

It was named ‘the secret to success’ by ABC news. Millions of people attest to its great efficiency and claim they would not be able to work the same way without it. It is said to be the go-to drug for improving concentration and reducing excessive sleepiness and chronic fatigue. Below is a comprehensive guide of the drug Provigil and all there is to know about its functions, dosage, side effects and its interaction with the human body.

 

WHAT IT IS:

Provigil is a drug that is said to promote wakefulness in adults. It was formulated in the late 1970s by Professor Emeritus and neurophysiologist Michael Jouvet and the Lafon Laboratories in France. It is sold as a prescription drug under the name Modiodal in France, Modavigil in Australia and Switzerland and Provigil in the USA and the UK. There is no official research conducted on the specific way that this drug works. However, a largely accepted theory is that Provigil alters the neurotransmitters in the brain which are chemical substances that aid in the transfer of impulses from the brain to the body and vice versa.

 

WHAT IT IS USED FOR:

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Officially, Provigil is used to treat sleep-related diseases such as Obstructive Sleep Apnea (OSA), Narcolepsy and Shift Work Disorder (SWD). OSA is the condition in which a person stops breathing temporarily during sleep. Narcolepsy is a neurological disorder that often causes excessive daytime sleepiness. SWD is a sleep disorder that is caused by disturbances in the human internal clock. It is usually found in people who work night shifts or rotating shifts. It is important to note that Provigil will treat but not cure these diseases caused by excessive sleepiness. This drug is only used to temporarily relieve the symptoms of the conditions listed above so ask your doctor if you are interested in a more permanent solution. Other off-record uses for Provigil include the treatment of fatigue and the enhancement of concentration.

 

BENEFITS:

Provigil is effective in improving alertness and wakefulness in adults. Most people find that taking Provigil helps them to keep their focus for longer hours and to also be generally What is the Perfect Dosage of Provigilalert hours after they take the drug.A study by the University of Cambridge shows that Provigil is effective in reducing ‘impulsive decisions’. Provigil is also known to improve cognitive responses and moods, induce motivation, reduce reaction time and enhance vigilance.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2654794/

https://examine.com/supplements/adrafinil/

http://www.studydrugs.net/Adrafinil-Review.html

DOSAGE:

For Narcolepsy and OSA, 200mg of Provigil must be take daily in the morning. For SWD, 200mg of Provogil must be taken an hour before the start of a night shift. Note that this is the usual dosage for adults but it can differ according to individual conditions. Run it past your doctor to find out the specific dosage required for your condition. Also note that Provigil is not FDA approved for children under 17 years and there is therefore no published dosage for this age range.

 

SIDE EFFECTS of Modafinil

The known side effects of Provigil are skin rash that can sometimes be severe enough for medical attention, back pain, headaches or dizziness and stuffiness in nose. It is advised to immediately stop the use of Provigil if any of the following side effects are noticed:

  1. Darkened urine and yellowing of the eyes and skin
  2. Mouth and throat sores

3.Swelling in legs, throat, eyes, face, tongue or lips

4.Blisters or peeling skin

  1. Fever
  2. Depression and anxiety
  3. Hallucination
  4. Chest pain

 

LONG TERM USE:

There is no official published data on the long-term effects of Provigil. However, Dr. Peter Morgan of Yale University suggests that Provigil may have the same long-term effects as Nicotine. The same way that Nicotine starts off as a cognitive enhancer but after several uses becomes a cognitive normalizer, Morgan thinks that there is no reason to believe that Provigil will be any different after long-term use. He also states that a possible long-term use may cause deficits in slow-wave sleep of users. It has also been reported that Provigil may very rarely cause dependence or addiction in some users. Consult your doctor to find out how long you should take prescribed Provigil for.

 

USE IN SILICON VALLEY:

TechCrunch reports that Provigil is seen as the new ‘entrepreneurs drug of choice’ following more common stimulators such as Aderall and caffeine. It is also reported that most entrepreneurs in the Silicon Valley that confess to the usage of Provigil use it regularly to work twenty hour shifts daily to give themselves and their businesses a competitive edge. Th preference of this drug over caffeine stems from the fact that it has cognitive benefits as opposed to just alertness like caffeine.

 

HOW TO USE PROPERLY:

Provigil must be used in the correct dosage as shown in the sections above. Some symptoms of overdosage of Provigil include:

  1. Insomnia or troubled sleep
  2. Increased blood pressure
  3. Overexcitement and anxiety
  4. Elevated heartbeat rate

 

DANGERS:

Provogil can cause serious dangers to people with:

  1. Angina (chronic chest pain)
  2. History of cardiac arrest
  3. High blood pressure and other heart diseases
  4. Cirrhosis and other liver conditions
  5. Psychosis and history of other mental conditions
  6. History of alcoholism or drug addiction

If any of these apply to you, tell your doctor before you start taking Provigil. The effects of fetuses is not known so tell your doctor if you are pregnant or have plans to get pregnant.

 

Provigil is a good choice for the treatment of sleep related diseases and improvement of concentration and alertness. Talk to your doctor before you start using Provigil to get a safe dosage for your individual condition. Also, report any side effects to your doctor as soon as you notice them.

Sources: 

  1. https://clinicaltrials.gov/ct2/show/NCT02886130
  2. https://www.ncbi.nlm.nih.gov/pubmed/1662399
  3. https://www.ncbi.nlm.nih.gov/pubmed/1409797

*Disclaimer: Statements found within have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease. Always consult a physician if you are unsure about taking a new supplement. Do not take this supplement if you are under 18, if you are pregnant, nursing, or have any cardiovascular issues. Scientific studies cited are not conclusive and have limitations, due to of their closed environment nature. Referenced studies will not necessarily determine your experience with a supplement, since there are many unaccounted variables, which fall outside the scope of the studies. All refunds must be brought to our attention within 7 days of delivery in order to be considered for reimbursement

Adrafinil for Depression

Adrafinil for Depression and Anxiety

 

Adrafinil is one of many nootropic supplements that people take today for the sake of increasing their cognitive performances and staying awake for an extended period of time. It’s similar to Modafinil, but the differences are extensive enough that people frequently compare the two supplements. Adrafinil is commonly used for depression to uplift one’s mood.

 

Benefits

 

Adrafinil is better at keeping people awake than almost any supplement people are going to find on the market today, and that includes very popular remedies like caffeine. In addition to the fact that this is a supplement that can keep people awake for around twelve hours or more, this is also a supplement that can keep people awake without many of the associated feelings of restlessness.

 

Adrafinil is also good at helping people with their mental concentration. People who take Adrafinil often feel more motivated. They are usually able to think more clearly because Adrafinil can help decrease brain fog and many of the mental effects of exhaustion. When added together, the effects of Adrafinil can really make it easier for people to complete projects and assignments.

 

Dosage to use of Adrafinil for Depression

 

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A low dosage for Adrafinil would be 300 mg a day, which will usually equate to one Adrafinil for Depressioncapsule. On the high end, people might take four capsules, or 1,200 mg a day. It’s not a good idea to exceed 1,200 mg, and most people should take 300 mg a day instead.

 

Side Effects

 

Most of the immediate side effects of Adrafinil are not going to be extreme. People who take Adrafinil might be at an increased risk of developing nausea, diarrhea, and problems with insomnia. Some mood effects of Adrafinil might include irritability or feelings of nervousness.

 

How to use Adrafinil for Depression

 

It’s a good idea to take Adrafinil a little bit before it becomes important to have a twelve-hour stretch of feeling energetic and sharp. People who are going to stay up all night, for instance, might want to take the Adrafinil in the early evening or late afternoon.

 

Long-term Adrafinil Use for Depression, Research on the Subject

 

It’s important for people to take Adrafinil only when they really need it, and not as part of their regular rotation. People should generally not consume Adrafinil like coffee. It’s not something that anyone should just use in order to wake up on a normal day. People will build up a tolerance to it that way, and taking ever-increasing amounts of Adrafinil in order to combat drug tolerance is a particularly bad idea. The risks associated with Adrafinil and liver toxicity are noteworthy enough that people should try to manage their Adrafinil consumption.

Checkout these links for further research:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2654794/

https://examine.com/supplements/adrafinil/

http://www.studydrugs.net/Adrafinil-Review.html

Adrafinil Liver toxicity concerns

 

Many people avoid taking Adrafinil due to the liver toxicity concerns. Adrafinil has been known to increase a person’s liver enzymes. However, people who do not take Adrafinil all the time and who only take it for a short period of time are probably going to be safe.

 

Research on Adrafinil for Depression

 

Adrafinil can help people with sleep disorders like narcolepsy and shift work sleep disorder, which has been demonstrated in clinical settings. This supplement may also be able to help people with certain learning disabilities, such as ADD.

 

Adrafinil vs Modafinil

 

Modafinil and Adrafinil are similar enough that people might feel as if one nootropic supplement could substitute for the other, and that might be true for the most part. It is generally believed that Modafinil is going to be the stronger of the two, and Modafinil does usually start taking effect after a shorter period of time. However, the effects of both of these will generally be similar, and that should make the substitution easier.

 

Adrafinil compared to other nootropics

 

Adrafinil is one of the most potent nootropics that people can take in general, which is one of the reasons why it is so popular. Some nootropics offer more of an array of cognitive benefits compared to Adrafinil. Adrafinil primarily helps with energy, motivation, and focus, thus allowing people to improve their learning indirectly rather than directly. However, this should be enough for some patients.

 

Conclusion

 

Adrafinil is a very strong and effective nootropic supplement that is very popular in the nootropics community for a reason. While people should not take it all the time, it is still a supplement that may be able to help people out at different points throughout their working or academic lives.

Sources: 

  1. https://clinicaltrials.gov/ct2/show/NCT02886130
  2. https://www.ncbi.nlm.nih.gov/pubmed/1662399
  3. https://www.ncbi.nlm.nih.gov/pubmed/1409797

*Disclaimer: Statements found within have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease. Always consult a physician if you are unsure about taking a new supplement. Do not take this supplement if you are under 18, if you are pregnant, nursing, or have any cardiovascular issues. Scientific studies cited are not conclusive and have limitations, due to of their closed environment nature. Referenced studies will not necessarily determine your experience with a supplement, since there are many unaccounted variables, which fall outside the scope of the studies. All refunds must be brought to our attention within 7 days of delivery in order to be considered for reimbursement

What is the Best Dosage of Adrafinil to Take for Long-Term Brain function?

What is the Best Dosage of Adrafinil to Take?

What is Adrafinil?

 

Adrafinil is a wakefulness promoting substance which belongs to the eugeroic group. A prodrug for modafinil, adrafinil leads to increased concentrations of modafinil in the body. Adrafinil is classified as a stimulant as it helps to fight exhaustion, sleepfulness, and fatigue for longer durations of time. Therefore, it is commonly used by people who work long night shifts or prolonged hours. A highly powerful compound, the drug also provides some nootropic effects such as improvement in overall brain function, increase in learning ability, and improved memory. The best dosage of Adrafinil to take, for both experienced users and those trying it for the first time, is typically 1, 300 milligram capsule.

Benefits

 

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There are several benefits associated with taking adrafinil, many of which are along the same lines as modafinil. Generally, the drug is taken when people require higher levels of alertness and mental focus or they are feeling very tired and need to stay awake. The main benefits of adrafinil include:

l Stimulation. As the drug is a stimulant it produces increases in stamina, attention, and energy levels.

l Productivity. A result of the increase in energy and motivation provided by adrafinil, productivity is often cited as a benefit of the drug.

l Cognitive Benefits. Other benefits such as an increase in memory and learning ability are also associated with adrafinil.

Dosage

 

The ideal dosage of adrafinil is between 600 and 1200mg. The substance is water soluble and can be taken on an empty stomach with either water or juice. Generally, it is taken in the morning since taking the drug in the afternoon, evening, or at night can cause insomnia. When first taking adrafinil it is recommended to begin with lower quantities and gradually increase your dosage to the higher end of the recommended dosages. Adrafinil should only be taken as an occasional drug or on a cyclic basis. For instance, when a deadline has to be met or take the drug for two weeks then a break for one week.

Side Effects

 

Common symptoms of the drug include stomach problems, headaches, and elevated blood pressure. If a high dosage of adrafinil is regularly taken, side effects could also include a reduction in the frequency of urine. Prolonged use of the drug can also result in other side effects such as liver damage, kidney failure, epilepsy, daydreaming, and hallucination. However, adrafinil also has positive side effects such as the cognitive properties displayed by people who take the drug including added motivation levels and energy levels, increased memory, and a higher level of learning ability.

How to use Adrafinil

 

When beginning to take adrafinil, always start at the lowest recommended dosage and work your way up after your body has had a chance to adjust. The powder can be taken with water or juice and it is high recommended to take it early in the day to avoid insomnia. When taking the drug, make a plan to take in cycles as prolonged or long term use is not recommended. A cycle of two weeks on and one week off helps to prolong the effects of the drug without your body building up a high tolerance level. Also, ensure you keep track of your liver function when taking the drug as the supplement is known to elevate enzymes within the liver which could lead to damage in the future.

Long-term Adrafinil Use

 

Adrafinil is not designed for long term use and is instead better taken in cycles. If you take What is the Best Adrafinil Dosage to Take?adrafinil for an extended period of time without using cycles, your body may develop tolerance against the drug and render its effects useless. Long term usage of adrafinil can also lead to behavioral changes such as laconic people becoming more talkative.

Adrafinil Liver toxicity concerns

 

If the recommended dosage of adrafinil is taken in cycles, there is little or no evidence of major liver concerns. However, the process of breaking adrafinil down into the liver and converting it into other ingredients is something which can cause damage in the long term. If you are taking the drug only a couple of time per week it is extremely unlikely you will notice a spike in your liver enzymes. If you are taking it on a more regular basis you may notice a slight increase in your liver enzymes, however, there is no evidence to suggest this will turn into long term damage. Although it is highly unlikely that any long term damage will occur, it’s important to consult your doctor if you have any concerns.

Research on Adrafinil

https://www.drugs.com/sfx/modafinil-side-effects.html

http://www.rxlist.com/provigil-side-effects-drug-center.htm

http://www.webmd.com/drugs/2/drug-16962/modafinil-oral/details/list-sideeffects

https://www.drugs.com/sfx/modafinil-side-effects.htm

http://www.rxlist.com/provigil-side-effects-drug-center.htm

http://www.webmd.com/drugs/2/drug-16962/modafinil-oral/details/list-sideeffects\

https://www.drugs.com/sfx/modafinil-side-effects.html

http://www.rxlist.com/provigil-side-effects-drug-center.htm

http://www.webmd.com/drugs/2/drug-16962/modafinil-oral/details/list-sideeffects

A major study of adrafinil was conducted in 2013 with the aim of determining whether the drug only improves cognitive functions in people who are deprived of sleep. The study used healthy people who were not suffering from lack of sleep and gave them a dose of 200mg of adrafinil. The participants then performed tasks which were designed to test their memory, creativity, and ability to problem solve. The results showed that those who were given adrafinil performed better than those who were not given the drug.

Adrafinil vs Modafinil

 

While both supplements are similar they are not entirely identical. Some reports say that the same dose of adrafinil is marginally less effective than modafinil. However, an important difference is that the effects of adrafinil are spread out over a longer period of time than those of modafinil. Also, adrafinil converts to modafinil when it is being processed by the body and it stands to reason the person taking adrafinil will benefit from the effects of modafinil as well as adrafinil.

Adrafinil compared to other nootropics

 

Other nootropics such as piracetam are much safer than adrafinil as they do not cause a feeling of burnout after the supplement has been taken. Also, many other nootropics possess greater neuroprotective qualities and work towards a healthier brain and better brain functions.

Conclusion

 

Adrafinil trumps other drugs which are created to act as stimulants as it not only provides a lot of energy but also focuses you by helping the brain assimilate information more efficiently. However, when compared to other nootropics, adrafinil falls slightly short. This is mainly due to the long term side effects of the drug and the fact that it must be taken in cycles or occasionally whereas other nootropics don’t carry this setback. Having said that, adrafinil is a great supplement for those working occasional night shifts or those who have a deadline to make and want to both stay awake and benefit from increased productivity.

Sources: 

  1. https://clinicaltrials.gov/ct2/show/NCT02886130
  2. https://www.ncbi.nlm.nih.gov/pubmed/1662399
  3. https://www.ncbi.nlm.nih.gov/pubmed/1409797

*Disclaimer: Statements found within have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease. Always consult a physician if you are unsure about taking a new supplement. Do not take this supplement if you are under 18, if you are pregnant, nursing, or have any cardiovascular issues. Scientific studies cited are not conclusive and have limitations, due to of their closed environment nature. Referenced studies will not necessarily determine your experience with a supplement, since there are many unaccounted variables, which fall outside the scope of the studies. All refunds must be brought to our attention within 7 days of delivery in order to be considered for reimbursement

Armodafinil vs Provigil vs Modalert

Armodafinil vs Provigil vs Modalert

Problems with sleep and sleep disorders can weigh heavily on a person’s ability to function and get through everyday activities. With all the prescription drugs and herbal remedies available today, it is difficult to know what to look for. The first step should always be a consultation with a medical professional to go over options. Armodafinil is a drug that is used in treating certain sleep conditions and also aids in improving concentration. When comparing Armodafinil vs Provigil vs Modalert, while they are all similar, Armodafinil is the obvious choice.

 

What Is Armodafinil?

 

Armodafinil is a drug that promotes focus and wakefulness. It was approved by the FDA in June of 2007 and has been helping people remain active and productive ever since. This drug may be useful for anyone who requires extra energy to stay focused throughout the day.

 

Benefits

 

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Armodafinil is used to treat patients with excessive daytime fatigue. This medication will Armodafinil vs Provigil vs Modalertprovide extra energy and help people stay awake so they can have a normal and productive day. Armodafinil also enhances mental performance for anyone who needs help completing daily tasks.

 

Dosage

 

The recommended dosage for Armodafinil in adults in 150 to 250 mg. It should be taken once in the morning and will last all day. Most people can take up to 250 mg, but studies have shown that, aside from being taken for a specific medical condition, there is no extra benefit to taking more that 150 mg. Compared to Modafinil, with a dosage of 1-200 milligrams at a time.

 

Long-Term Use

 

There have been many tests performed on people who have taken Armodafinil over a long period of time, and there have been no reports of any negative long term effects. The substance may however be habit forming and should only be used as prescribed by a doctor.

 

How to Take

 

Armodafinil should be taken once a day, orally. If it is being taken for excessive fatigue during the work day it is usually recommended to be taken one hour before the work day starts. Modalert and Provigil should be taken in much the same fashion.

 

What is Armodafinil Used For?

 

The primary use of Armodafinil is to give some relief to those who constantly feel as though they need more sleep. Many people also use this medication to focus and complete activities. The boost in energy and clear thinking will make sure everyday is just as productive as it needs to be.

You can checkout these URLS for further research on the drug

https://www.drugs.com/sfx/modafinil-side-effects.html

http://www.rxlist.com/provigil-side-effects-drug-center.htm

http://www.webmd.com/drugs/2/drug-16962/modafinil-oral/details/list-sideeffects

https://www.drugs.com/sfx/modafinil-side-effects.htmhttp://www.rxlist.com/provigil-side-effects-drug-center.htm

http://www.webmd.com/drugs/2/drug-16962/modafinil-oral/details/list-sideeffects\

https://www.drugs.com/sfx/modafinil-side-effects.htmlhttp://www.rxlist.com/provigil-side-effects-drug-center.htm

http://www.webmd.com/drugs/2/drug-16962/modafinil-oral/details/list-sideeffects

 

Side Effects

 

 Common side effects when taking Armodafinil may include headache, dry mouth, upset stomach, dizziness, anxiety and difficulty sleeping. More serious, less common side effects include fever, sore throat, mouth sores, trouble swallowing, easy bruising or bleeding, chest pain, uneven heartbeats, loss of appetite, and vomiting. Discontinue use and contact a doctor immediately if symptoms such as hives, difficulty breathing, or swelling occur as they could be signs of an allergic reaction.

 

Effects

 

When taken as directed, Armodafinil will alleviate constant fatigue in patients who are looking for an answer to shift work disorder. Unlike caffeine, it will give an alertness without the excessive jitters that come along with a few cups of coffee. When being taken for narcolepsy it will greatly improve quality of life by making sure patients can stay active without the need for excessive napping or use of stimulants. People using Armodafinil for increased productivity will see an increase in concentration and will be able to focus easily for longer periods of time.

 

Dangers

 

Armodafinil may become habit forming. Make sure to speak with a doctor if there is any history of drug or substance abuse. If being taken for sleep disorders, the higher dosage of 200-250 mg is normal, if however the medication is being taken for concentration and focus the dosage should stay between 100-150 mg. When used as directed the risk of dependency is greatly lowered.

 

Research

 

Occasionally being referred to as a “smart drug,” Armodafinil has been shown to help with clarity of mind. Unlike Adderall, a very strong medication with harsh side effects, Armodafinil has been shown to help concentration without being heavily medicated. Many have stated that their productivity has increased dramatically with regular use. There have also been recent studies that show Armodafinil may be useful to treat jet lag. The study is aiming to use Armodafinil to rid the hazy sleepy feeling that comes along with switching time zones which would be incredibly helpful to those who travel often.

 

What is Armodafinil Prescribed For?

 

Armodafinil is commonly prescribed in the treatment of narcolepsy and shift work disorder. It has also been known to be used in conjunction with other treatments for obstructive sleep apnea. People with sleep disorders such as these have shown drastic improvement in their lifestyles after being prescribed Armodafinil.

 

Conclusion

 

For anyone who suffers with constant fatigue or lack of concentration, Armodafinil may be able to help. The FDA has approved Armodafinil to be used by anyone with a prescription from their doctor. The advantages of this medication include increased activity and brain function. When used as directed, anyone will see their quality of life improve immensely.

 

Sources:

“Nuvigil (Armodafinil) Drug Information: Description, User Reviews, Drug Side Effects, Interactions – Prescribing Information at RxList.” RxList. 27 Apr. 2015. Web. 02 May 2016.

“Can Nuvigil Cause Withdrawal, Abuse, Tolerance or Addiction?” Nootriment. 2014. Web. 02 May 2016.

*Disclaimer: Statements found within have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease. Always consult a physician if you are unsure about taking a new supplement. Do not take this supplement if you are under 18, if you are pregnant, nursing, or have any cardiovascular issues. Scientific studies cited are not conclusive and have limitations, due to of their closed environment nature. Referenced studies will not necessarily determine your experience with a supplement, since there are many unaccounted variables, which fall outside the scope of the studies. All refunds must be brought to our attention within 7 days of delivery in order to be considered for reimbursement

 

What are Nootropics?

What are Nootropics, and How do they Benefit the Brain?

What are nootropics?

 

Nootropics is a general term which is used to describe both naturally occurring and manmade chemicals that enhance cognitive function to the human brain. Also known as a smart drug or cognitive enhancers, nootropics act to increase a range of functions including memory, mood, motivation, concentration, and almost anything else that is related to thought and cognition. To be classified as a nootropic a chemical must be safe and pose extremely low risk of side effects when used as directed and appropriately.

What are the top nootropics?

 

Nootropics broadly fall into four categories or groups:

 

Racetams – Racetams are a group which began with the discovery of piracetams, known as the “father of nootropics”. The discovery of piracetams led to a number of other nootropics being designed including aniracetam, oxiracetam, pramiracetam, and noopept. The main effects of racetams is an improvement in memory and increased learning ability.

Choline Supplements – Bioavailable forms of choline such as GPC and CDP choline What are Nootropics?both nourish the brain and provide it with the building materials for cell membrane synthesis and acetylcholine.

Herbs – Herbs which traditionally were used for thousands of years to reduce stress, support cognitive function, and strengthen the mind are also known as nootropics. These include bacopa, ginkgo, huperzine-a, and vinpocetine.

Modified Nutrients and Vitamins – Manmade semi-synthetic forms of vitamins B1 and B6, such as sulbutiamine and pyritinol, both have cognitive enhancing qualities.

Benefits of nootropics

 For research on nootropics and Modafinil, checkout these links for further info: 

https://www.theguardian.com/science/2015/aug/20/narcolepsy-medication-modafinil-worlds-first-safe-smart-drug

http://www.pharmaceutical-journal.com/news-and-analysis/modafinil-could-be-the-first-safe-smart-drug/20069223.article

https://qz.com/485020/the-worlds-first-true-smart-drug-enhances-cognition-and-is-deemed-safe-by-health-experts/

https://medlineplus.gov/druginfo/meds/a602016.html

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3286657/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2654794/

Due dilligence is crucial when experimenting with any new brain supplement, so always do your own research beforetrailing.

Since the agricultural revolution 10,000 years ago, humans have increasingly had to deal with more and more information. Due to this, people today suffer from stress, tiredness, memory loss, and other symptoms caused by the demands of modern life. Nootropics help ease the demands by increasing memory and the ability to learn new information, protecting the brain from physical and chemical assaults, aiding brain function, and increasing the efficiency of neuronal firing control mechanisms. This in turn leads to less stress, more energy, and a better quality of life.

Side effects of nootropics

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One of the main criteria that a chemical must meet before it is classified as a nootropic is that it must show little to no side effects. Nootropics are known as some of the safest supplements on the market today and there are no known complications when taking nootropics safely and appropriately. There is also no risk of addiction or withdrawal symptoms when taking nootropics. However, some possible side effects of taking nootropics include headaches, anxiety, insomnia, and fatigue. If any of these are experienced you should consult your doctor.

Research on nootropics

 

While research on the long-term effects of some types of nootropics is limited, particularly on many non-pharmaceuticals and newly developed pharmaceuticals, there is data on racetams available. Studies of racetams show that there are few serious adverse effects and that addiction is very rare in people who take these supplements.

Examples of the top nootropics

 The best Nootropics Available

Some of the top nootropics include:

 

Piracetam – Known as the “father of nootropics”, Piracetam was the original nootropic substance and is the foundation for many of the nootropics available today. Designed to improve cognition, piracetam provides memory boost, increased learning ability, and even reduced aggression.

PhenibutA slightly different form of nootropic, phenibut is extremely powerful at promoting tranquil and calm states. While other nootropics generally promote stimulation within the brain, phenibut improves memory and cognition while also working as an anti-anxiety substance.

Choline Bitartrate – The “salt” form of choline, choline bitartrate is stable and easy to digest. As well as acting to improve memory and cognitive performance, the substance also features powerful anti-oxidant and anti-inflammatory properties.

Noopept – The strongest nootropic available, Noopept is up to 1,000 times stronger than piracetam. The main effects of the substance include increased learning capacity and increased memory as well as strong anti-anxiety effects.

Nootropics vs Modafinil

 

Modafinil is classified as a eugeroic, meaning it promotes alertness and reduces feelings of tiredness. There are several potentially dangerous side effects associated with modafinil including allergic reactions, difficulty when breathing, and irregular heartbeat. However, side effects associated with nootropics are mild and well tolerated such as insomnia, increased libido, and some mild irritability. While modafinil is occasionally used off-label as a cognitive enhancement, it does not promote brain function without major side effects as one would find in nootropics.

What nootropics are best?

 

The best nootropics are designed very specifically to aid in certain fields. Therefore, depending on what you want to achieve, you would take certain nootropics or even create a nootropic stack. Nootropic stacks mix a few supplements together to achieve results faster and also affect several different dynamics of brain function at the same time, rather than a single brain function by using a single nootropic. Some of the most popular nootropics for better overall cognitive performance and energy include:

l Noopept

l Alpha-GPC

l Piracetam

l Pramiracetam

l Vinpocetine

How should a newbie start with nootropics?

 

Many people start taking nootropics with the aim of achieving a certain goal, whether that is focusing more on work, reducing anxiety, studying for school, or a multitude of other reasons. However, this often leads to people taking higher quantities of nootropics than recommended. The most important rule for newbies to nootropics is to take the recommended dosage from the beginning. Allow yourself to ease into taking nootropics with a particular goal in mind. Many people jump straight in to nootropic stacks at the beginning, however, the reality is you may only need to take one nootropic to achieve the results you desire. Start slowly and build up if required.

Final Thoughts on nootropics

 

Nootropics use is continually growing and receiving more and more media attention online. The reason for the increase in consumption and attention is the huge benefits brought about by these substances. Enhancing brain and cognitive function without side effects is truly a wonderful thing. To date, studies conducted on nootropics have shown no substantial short or long term side effects and have proved that nootropics really do work. In fact, current analysis of the chemical is looking into the effects it may have on major brain malfunctions and if nootropics could aid in repairing these problems. However, as with any substance it is highly recommended that you never overdose on nootropics and only take dosages as recommended.

Sources: 

  1. https://clinicaltrials.gov/ct2/show/NCT02886130
  2. https://www.ncbi.nlm.nih.gov/pubmed/1662399
  3. https://www.ncbi.nlm.nih.gov/pubmed/1409797

*Disclaimer: Statements found within have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease. Always consult a physician if you are unsure about taking a new supplement. Do not take this supplement if you are under 18, if you are pregnant, nursing, or have any cardiovascular issues. Scientific studies cited are not conclusive and have limitations, due to of their closed environment nature. Referenced studies will not necessarily determine your experience with a supplement, since there are many unaccounted variables, which fall outside the scope of the studies. All refunds must be brought to our attention within 7 days of delivery in order to be considered for reimbursement

Adrafinil for Focus, Memory and Brain Function

Adrafinil for Focus, Memory and Brain Function?

 

Adrafinil is a popular nootropic supplement that is similar to Modafinil. People take both of these supplements in order to stay awake and to improve their standards of cognition while they are awake. However, these are supplements that help people make the most of their extended waking hours as well.

 

Benefits

 

Patients are going to take Adrafinil for a lot of different reasons, but they’re primarily going to take it in order to become more energetic. This is a supplement that can help people regulate their sleep cycle, allowing them to stay awake for a longer period of time. People who have been awake for more than sixteen hours can find that their feelings of fatigue and sluggishness will evaporate as soon as the effects of Adrafinil set in for them.

You can learn more on the drug and Modafinil comparisons at the following research links

https://www.drugs.com/sfx/modafinil-side-effects.htmlhttp://www.rxlist.com/provigil-side-effects-drug-center.htm

http://www.webmd.com/drugs/2/drug-16962/modafinil-oral/details/list-sideeffects

https://www.drugs.com/sfx/modafinil-side-effects.htm

http://www.rxlist.com/provigil-side-effects-drug-center.htm

http://www.webmd.com/drugs/2/drug-16962/modafinil-oral/details/list-sideeffects\

https://www.drugs.com/sfx/modafinil-side-effects.html

http://www.rxlist.com/provigil-side-effects-drug-center.htm

http://www.webmd.com/drugs/2/drug-16962/modafinil-oral/details/list-sideeffects

 

However, while a lot of stimulant supplements are going to cause a person to become anxious and jittery, with Adrafinil, that energy gets channeled in more positive and Adrafinil for focus and memoryproductive directions. People should find it easier to stay focused and to work thanks to their Adrafinil regimens and not harder.

 

Many people who take Adrafinil are going to find it easier to stay motivated. They will be able to pay attention to various tasks at hand for a longer period of time. Many people find that their output will increase as a result of their Adrafinil regimens, partly owing to the fact that they are more energized and focused, and partly due to the fact that Adrafinil can make some people think more creatively.

 

Dosage

 

Patients are going to take between 300 mg and 1,200 mg of Adrafinil on a daily basis in order to get the results. People who have more of a tolerance level are going to need to take a larger dose in most cases. Most people who are still starting out with Adrafinil should maintain a lower dosage. They will be able to get the results that they want at the lower dosages, and they will also absorb fewer risks in general in the process.

 

Side Effects

 

The majority of the short-term side effects of Adrafinil are fairly minor. Stimulant supplements like Adrafinil often cause a loss of appetite, because the body is under the impression that it is getting fed as a result of the new surplus of energy.

 

Adrafinil can also cause other digestive side effects, such as nausea and diarrhea. Some people will experience headaches, dry mouth, unexplained pains, feelings of numbness, nervousness, a difficulty sleeping, and orofacial dyskinesia. The long-term risks of persistent and consistent Adrafinil consumption are much more worrying.

 

How to use Adrafinil

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The effects of Adrafinil can last for a long time. Some people won’t experience the effects for more than an hour after taking the Adrafinil, but the effects could last for as long as twelve hours or more. It’s a good idea for people to be able to time their Adrafinil consumption correctly.

 

They should make sure that they are not going to need the effects of the supplement right away when they take it, since they might get the energy benefits after they have become obsolete as a result. They should also try to save their Adrafinil supplements for when they really need them, given the potential risks associated with these supplements over the long-term.

 

Long-term Adrafinil Use

 

Adrafinil is not recommended for long-term use. This is a supplement that can raise a person’s liver enzymes over time, and this is going to raise a person’s risk of developing various liver problems. With almost all long-term drug use, building up a tolerance is also going to be a concern as well. People aren’t going to want to take so much Adrafinil that it more or less stops working for them.

 

Adrafinil Liver Toxicity Concerns

 

It is true that Adrafinil is capable of raising the body’s liver enzymes. People who use this nootropic over the long-term on a very regular basis might be in a situation where they’re going to cause themselves liver damage. However, it should at least be noted that people who take over-the-counter medications like Advil and Tylenol can do the exact same thing. People should be wary of the risks while keeping them in perspective.

 

Research on Adrafinil

 

While Adrafinil has not been subject to as much research as Modafinil, this is still a supplement that has been researched to a certain extent. Adrafinil has been shown to have some benefits for sleeping disorders, such as narcolepsy and shift work sleep disorder. Adrafinil also has benefits for people who are suffering from problems with ADD and ADHD.

 

Adrafinil vs Modafinil

 

Many people say that Adrafinil does not quite have the strength and potency of Modafinil, and that is the result that many people have gotten. Lots of people are also going to find that Adrafinil will take longer to go into effect compared with Modafinil. However, the two of them do have many of the same cognitive benefits and many of the same side effects. Modafinil may be the stronger of the two, but Adrafinil still might ultimately give people similar results.

 

Adrafinil compared to other nootropics

 

Adrafinil has a wider range of effects compared to many other nootropics. Some of the long-term side effects of Adrafinil, such as the liver toxicity, are not observed in other nootropics. The cost and benefit analysis at the heart of Adrafinil might be somewhat different for a lot of people. Nootropics vary in terms of their main effects and side effects. Adrafinil is certainly one of the most effective stimulant nootropics that people will find.

 

Conclusion

 

Adrafinil is a solid nootropic supplement that should manage to give people the effects that they need when they most need them. It is true that this is a supplement that carries some real risks. However, most medications have risks of some kind, and as long as people don’t use Adrafinil too frequently, they should be able to get most of the benefits with few of the costs.

Sources: 

  1. https://clinicaltrials.gov/ct2/show/NCT02886130
  2. https://www.ncbi.nlm.nih.gov/pubmed/1662399
  3. https://www.ncbi.nlm.nih.gov/pubmed/1409797

*Disclaimer: Statements found within have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease. Always consult a physician if you are unsure about taking a new supplement. Do not take this supplement if you are under 18, if you are pregnant, nursing, or have any cardiovascular issues. Scientific studies cited are not conclusive and have limitations, due to of their closed environment nature. Referenced studies will not necessarily determine your experience with a supplement, since there are many unaccounted variables, which fall outside the scope of the studies. All refunds must be brought to our attention within 7 days of delivery in order to be considered for reimbursement

What are the Best Choline Sources when Taking Nootropics?

What are the Best Choline Sources When Taking Modafinil and Nootropics?

Choline is a vital part of any cognitive maintenance and enhancement routine. Not only is choline a vital precursor to the learnning and memory neurotransmitter acetylcholine, it’s one of the most important brain nutrients. As if this wasn’t enough to make you check your choline intake, something like 90% of the population is already deficient in choline. Choline deficiency can be detrimental to optimal mental performance and even mood. Choline, though not considered a b-vitamin is closely chemically related to the b-complex of vitamins which serve an ancillary role in neuronal transmission and formation. The best Choline sources are typically CDP choline, Alpha GPC Choline, and Centrophenoxine.

Choline can be derived through the diet or in supplemental form. Dietary choline is often found in fish, eggs, soy and to a great degree in lecithin (which is found in soy, eggs and dairy). One of the highest quality choline sources is Alpha GPC (l-alpha glycerylphosphorylcholine). Long name for what is basically just a very highly refined form of lecithin. In addition to being a precursor to acetylcholine it has a number of added benefits.  Part of the magic of Alpha GPC is it’s bio-availability. It is readily absorbed through the blood-brain barrier.

What is Choline?

Unlike choline bitartrate or choline citrate (more expensive but lower quality choline sources). Since choline is water soluble,  the body can’t build up stores of it in fat so it must be continually ingested as it’s used by the brain. Choline on it’s own doesn’t have any stand-alone nootropic properties. Alpha GPC on the other hand has shown a parity with piracetam used without a choline source.

Certain studies suggest that boost in mood, increased endurance and strength output may be an added boon. As a result, it may be a suitable adjunct to a workout or strength What are the Best Choline Sources?training regimen. Acetylcholine, in addition to being a central compound involved in the brain’s memory consolidation, storage and recall processes (and as a result learning tasks in general) is involved in muscle contraction.

Fine motor movements, and the contraction of muscles is dependent on cascading of acetylcholine (the electro-chemical reaction set into play by acetylcholine). GPC may also stimulate human growth hormone release. Alpha GPC’s pituitary action should allow for development of muscle mass to be built more quickly. As if all this wasn’t enough, it can even be a detoxifying supplement as well as lowering cholesterol levels in the liver. As a liver cleanser, GPC could be especially helpful for those who are suffering from Diabetes or who have had some liver damage due to alcohol abuse.

Benefits and Research on Choline

Alpha GPC, like the structurally related b-vitamins, is necessary for nerve formation and healthy nervous system function.  The brain itself is composed of fatty material, phosphatidyl-choline and phosphatidyl serine, so the fatty, phospho-lipid GPC, the b-complex and our gray matter itself are very closely related physically. Speaking of lipidinous, be careful with GPC as a supplement. Pure GPC is highly hygroscopic, which means it picks up moisture from the air. If it isn’t combined with an excipient substance then it turns to an oily mess in room temperature at exposure to normal humidity conditions. Due to this, often you will find GPC sold in a 50% formulation. Pure GPC can even slowly degrade capsules once it turns to an oil.

You can look here for more information:

https://en.wikipedia.org/wiki/Alpha-GPC

https://psychonautwiki.org/wiki/Alpha-GPC

What are the tangible advantages of Alpha GPC over Choline Bitarate? from Nootropics

Choline itself is an essential nutrient and possesses no side effects or interactions. The most common negative effects reported would be some gastric distress possible with too high doses but in excess amounts choline may also have a negative effect on mood despite being somewhat anti-depressant in recommended doses. Always exercise healthy supplementation procedures. Minimum effective dosing and following guidelines for suggested use are recommended for this and all other cognitive enhancers.

Even if you’re just planning on switching to a high choline diet, make sure to check with your primary care practitioner. Any alteration of your diet, exercise regimen or supplementation routine should be run by your doctor especially if you’re currently under a physician’s care or taking any over the counter or prescription supplements for any preexisting condition.

Sources: 

  1. https://clinicaltrials.gov/ct2/show/NCT02886130
  2. https://www.ncbi.nlm.nih.gov/pubmed/1662399
  3. https://www.ncbi.nlm.nih.gov/pubmed/1409797

*Disclaimer: Statements found within have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease. Always consult a physician if you are unsure about taking a new supplement. Do not take this supplement if you are under 18, if you are pregnant, nursing, or have any cardiovascular issues. Scientific studies cited are not conclusive and have limitations, due to of their closed environment nature. Referenced studies will not necessarily determine your experience with a supplement, since there are many unaccounted variables, which fall outside the scope of the studies. All refunds must be brought to our attention within 7 days of delivery in order to be considered for reimbursement